Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760089 | 1.00 | APP (0.38) | APPMAPTACHEPTPN2PTPN1 | |
| SCHEMBL2636453 | 0.82 | MAPT (0.43) | APPMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL2636452 | 0.82 | MAPT (0.43) | APPMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL2636930 | 0.80 | APP (0.36) | APPMAPTACHEPTPN2PTPN1 | |
| SCHEMBL2636926 | 0.79 | APP (0.38) | APPMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL2636924 | 0.79 | APP (0.38) | APPMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL13003199 | 0.77 | MAPT (0.44) | APPMAPTPTPN2PTPN1PTPN6 | |
| SCHEMBL2637323 | 0.75 | CYP19A1 (0.54) | APPMAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL2637324 | 0.75 | CYP19A1 (0.54) | APPMAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1974701 | 0.67 | MAPT (0.48) | APPMAPTPTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | APP 1205/4885MAPT 1129/4885ACHE 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.