Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974701 | 0.84 | MAPT (0.48) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL1974700 | 0.84 | MAPT (0.48) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL2636844 | 0.83 | KDM4E (0.46) | MAPTAPPKDM4EKDM1ATRPV1 | |
| SCHEMBL2636843 | 0.83 | KDM4E (0.46) | MAPTAPPKDM4EKDM1ATRPV1 | |
| SCHEMBL2636400 | 0.82 | ACHE (0.48) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL2636189 | 0.82 | ACHE (0.48) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL3760090 | 0.77 | APP (0.38) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL3760089 | 0.77 | APP (0.38) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL13003198 | 0.76 | CYP19A1 (0.60) | MAPTAPPCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL13003197 | 0.75 | CYP1A1 (0.50) | MAPTAPPCYP1A1CYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | GENERAL ELECTRIC COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100310456-A1 | IMAGING OF MYELIN BASIC PROTEIN | MAG, PMP22, MYT1 | MAPT 1129/4885APP 1205/4885CYP1A1 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.