⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419917 | 0.91 | CCR2 (0.31) | — | |
| SCHEMBL16246596 | 0.89 | CCR2 (0.36) | — | |
| SCHEMBL9095092 | 0.86 | — | — | |
| SCHEMBL30915787 | 0.86 | — | — | |
| SCHEMBL30196745 | 0.86 | — | — | |
| SCHEMBL27467506 | 0.84 | NISCH (0.34) | — | |
| SCHEMBL22510032 | 0.83 | CCR2 (0.39) | — | |
| SCHEMBL918438 | 0.82 | NISCH (0.38) | — | |
| SCHEMBL6105380 | 0.82 | — | — | |
| SCHEMBL27451622 | 0.82 | NISCH (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1020 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429331-B | Chiral hexahydroindole derivative and preparation method thereof | 华东师范大学 | 2022-10-25 | — | — | CN | claimed |
| CN-113429331-A | Chiral hexahydroindole derivative and preparation method thereof | 华东师范大学 | 2021-09-24 | — | — | CN | claimed |
| EP-0672052-B1 | TACHYQUININE ANTAGONISTS, THEIR PREPARATION AND USE IN PHARMACEUTICAL FORMULATIONS | MENARINI FARMA IND (IT) | 1997-07-16 | — | — | EP | claimed |
| US-5641802-A | ANTAGONISTS OF SUBSTANCE P, NEUROKININ A, NEUROKININ B; TREATING RESPIRATORY, OPHTHALMIC, CUTANEOUS, INTESTINAL DISORDERS | A. MENARINI INDUSTRIE FARMACEUTICHE REIUNITE S.R.L. | 1997-06-24 | — | — | US | claimed |
| EP-0740656-A1 | TACHYKININS ANTAGONISTS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1996-11-06 | — | — | EP | claimed |
| EP-0731790-A1 | TACHYKININ ANTAGONISTS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1996-09-18 | — | — | EP | claimed |
| EP-0672052-A1 | TACHYQUININE ANTAGONISTS, THEIR PREPARATION AND USE IN PHARMACEUTICAL FORMULATIONS. | MENARINI FARMA IND (IT) | 1995-09-20 | — | — | EP | claimed |
| WO-1995019966-A1 | TACHYKININS ANTAGONISTS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1995-07-27 | — | — | WO | claimed |
| WO-1995015311-A1 | TACHYKININ ANTAGONISTS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1995-06-08 | — | — | WO | claimed |
| WO-1994013694-A1 | TACHYQUININE ANTAGONISTS, THEIR PREPARATION AND USE IN PHARMACEUTICAL FORMULATIONS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1994-06-23 | — | — | WO | claimed |
| EP-0243645-B1 | Compounds having a nootropic activity, agents containing them and their use in the treatment and prophylaxis of cognitive malfunctions | HOECHST AG (DE) | 1994-03-16 | — | — | EP | claimed |
| CN-1038096-A | Application with the compound of treatment psychosis effect, the reagent that contains this compounds and treatment thereof and prevention central nervous system disorder | HOECHST AG (DE) | 1989-12-20 | — | — | CN | claimed |
| EP-0089637-B1 | BICYCLIC AMINO ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR APPLICATION, BICYCLIC AMINO ACIDS AS INTERMEDIATES, AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-15 | — | — | EP | claimed |
| US-4562202-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | claimed |
| EP-0037784-A1 | Indolobenzoxazine derivatives, their salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1981-10-14 | — | — | EP | claimed |
| JP-5017474-A | — | — | None | — | — | JP | disclosed |
| WO-2025045746-A1 | PYRAZOLE DERIVATIVES AS SARM1 INHIBITORS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-03-06 | — | — | WO | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-4001248-A | ANALGETIC AGONIST AND ANTAGONIST | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001247-A | 1-ETHYL 3A-(SUBSTITUTED-PHENYL) DECAHYDROISOQUINOLINE | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |