Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.81 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907984 | 1.00 | HRH3 (0.81) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL1221877 | 1.00 | HRH3 (0.81) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL7737049 | 1.00 | HRH3 (0.81) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL16214678 | 1.00 | HRH3 (0.81) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL10445885 | 0.98 | HRH3 (0.77) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL8206597 | 0.92 | HRH3 (0.71) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL18059195 | 0.92 | HRH3 (0.69) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL8498722 | 0.91 | HRH3 (0.69) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL8499436 | 0.91 | HRH3 (0.69) | HRH3HSP90AA1FAAHALDH1A1MEN1 | |
| SCHEMBL7739091 | 0.90 | HRH3 (1.00) | HRH3FAAHALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305198-A1 | CATIONIC LIPIDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURG (GB) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305198-A1 | CATIONIC LIPIDS | CETP, LIPA, ABHD16A | HRH3 1740/4885HSP90AA1 4072/4885FAAH 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.