Sugi Predict

Sugi Predict / Compounds / SCHEMBL7737049

SCHEMBL7737049

SCHEMBL7737049

CCCCCCCCCCCCCCCC(=O)NC(CO)(CO)CO

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 1/20 0.81
▸ HSP90AA1 P07900 1/20 0.55
▸ FAAH O00519 6/20 0.53
▸ ALDH1A1 P00352 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ CES2 O00748 3/20 0.46
▸ CES1 P23141 3/20 0.46
▸ PPARG P37231 5/20 0.45
▸ PPARD Q03181 5/20 0.45
▸ PPARA Q07869 5/20 0.45
▸ HDAC11 Q96DB2 4/20 0.45
▸ TSHR P16473 3/20 0.45
▸ GPR84 Q9NQS5 3/20 0.45
▸ TLR2 O60603 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ FABP4 P15090 2/20 0.45
▸ PTPN1 P18031 2/20 0.45
▸ SLC22A6 Q4U2R8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2907984 1.00 HRH3 (0.81) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL1221877 1.00 HRH3 (0.81) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL16214678 1.00 HRH3 (0.81) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL3760754 1.00 HRH3 (0.81) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL10445885 0.98 HRH3 (0.77) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL8206597 0.92 HRH3 (0.71) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL18059195 0.92 HRH3 (0.69) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL8498722 0.91 HRH3 (0.69) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL8499436 0.91 HRH3 (0.69) HRH3HSP90AA1FAAHALDH1A1MEN1
SCHEMBL7739091 0.90 HRH3 (1.00) HRH3FAAHALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304605-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS SCIENTIFIC, INC. (US) 2025-10-02 — — US disclosed
US-12264170-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. (US) 2025-04-01 — — US disclosed
US-12134628-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. 2024-11-05 — — US disclosed
US-20240309026-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS SCIENTIFIC, INC. (US) 2024-09-19 — — US disclosed
US-12024533-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. (US) 2024-07-02 — — US disclosed
US-12024533-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. (US) 2024-07-02 — — US disclosed
US-12006338-B2 Antimicrobial organosilanes TOPIKOS SCIENTIFIC, INC. (US) 2024-06-11 — — US disclosed
US-20230295195-A1 ANTIMICROBIAL ORGANOSILANES Tipikos Pharmaceuticals, Inc. (US) 2023-09-21 — — US disclosed
US-20230295195-A1 ANTIMICROBIAL ORGANOSILANES Tipikos Pharmaceuticals, Inc. (US) 2023-09-21 — — US disclosed
US-20230143708-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS PHARMACEUTICALS, INC. (US) 2023-05-11 — — US disclosed
EP-4045057-A1 ANTIMICROBIAL ORGANOSILANES Topikos Pharmaceuticals, Inc. (US) 2022-08-24 — — EP disclosed
CN-114901291-A Antibacterial organosilanes 托皮科斯药品公司 2022-08-12 — — CN disclosed
WO-2021077119-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS PHARMACEUTICALS, INC. (US) 2021-04-22 — — WO disclosed
WO-2021077119-A1 ANTIMICROBIAL ORGANOSILANES TOPIKOS PHARMACEUTICALS, INC. (US) 2021-04-22 — — WO disclosed
EP-3229811-B1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GRI BIO INC (US) 2021-02-24 — — EP disclosed
EP-3229811-B1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GRI BIO INC (US) 2021-02-24 — — EP disclosed
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES CLARIA ODIN LLC 2018-02-01 — — US disclosed
WO-2016094226-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GLYCOREGIMMUNE, INC. (US) 2016-06-16 — — WO disclosed
US-20160158258-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS ALTIUM GROWTH FUND, LP 2016-06-09 — — US disclosed
US-6410597-B1 ANTIINFLAMMATORY AGENTS VIRGINIA COMMONWEALTH UNIVERSITY 2002-06-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304605-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-12264170-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-20240309026-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-12134628-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-12024533-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES PDK1, PC, PDK2 HRH3 3172/4885HSP90AA1 605/4885FAAH 4014/4885
US-20230143708-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-12006338-B2 Antimicrobial organosilanes ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-20230295195-A1 ANTIMICROBIAL ORGANOSILANES ARG1, ACMSD, AAAS HRH3 790/4885HSP90AA1 1012/4885FAAH 3503/4885
US-20160158258-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS RXRA, RXRG, CX3CR1 HRH3 1854/4885HSP90AA1 2326/4885FAAH 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.