SCHEMBL3760944

SCHEMBL3760944

C=C(C)C(=O)CCOc1ccc(C2(c3ccc(OCCC(=O)C(=C)C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.41
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
OPRK1 P41145 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534211 0.93 PDK2 (0.41) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL16425349 0.87 MAPT (0.41) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL535058 0.86 PDK2 (0.43) PDK2
Methacrylic Acid SCHEMBL23002863 0.84 GAA (0.46) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL30800968 0.84 POLB (0.48) PDK2MEN1MAPTKMT2AKDM4E
Methacrylic Acid SCHEMBL31331565 0.84 GAA (0.46) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL157502 0.84 POLB (0.48) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL2384274 0.83 PDK2 (0.44) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL534807 0.82 POLB (0.53) PDK2MEN1MAPTKMT2AKDM4E
SCHEMBL13962705 0.82 POLB (0.40) PDK2MEN1MAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183313-B2 Light guide including surface-treated resin OMRON CORPORATION (JP) 2012-05-22 US disclosed
US-20100304153-A1 SURFACE-TREATED RESIN, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME OMRON CORPORATION (JP) 2010-12-02 US disclosed
EP-2082872-A1 SURFACE-TREATED RESIN, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME OMRON Corporation, a corporation of Japan (JP) 2009-07-29 EP disclosed