Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAX | P61244 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997315 | 1.00 | MMP3 (0.53) | MMP3MMP13RAB9ANPC1MYC | |
| SCHEMBL3761292 | 1.00 | MMP3 (0.53) | MMP3MMP13RAB9ANPC1MYC | |
| SCHEMBL3763217 | 0.92 | PIM1 (0.52) | RAB9ANPC1POLB | |
| SCHEMBL3763213 | 0.92 | PIM1 (0.52) | RAB9ANPC1POLB | |
| SCHEMBL12997337 | 0.89 | CISD1 (0.50) | RAB9ANPC1MYCMAXDYRK1A | |
| SCHEMBL3761342 | 0.89 | CISD1 (0.50) | RAB9ANPC1MYCMAXDYRK1A | |
| SCHEMBL12997331 | 0.89 | PDE4B (0.57) | DYRK1AMEN1KMT2APIK3CGADAMTS5 | |
| SCHEMBL12997326 | 0.89 | PDE4B (0.48) | MMP3MMP13RAB9ANPC1MYC | |
| SCHEMBL3761343 | 0.89 | CISD1 (0.50) | RAB9ANPC1MYCMAXDYRK1A | |
| SCHEMBL3765526 | 0.89 | MMP3 (0.55) | MMP3MMP13RAB9ANPC1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305174-A1 | Novel Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-12-02 | — | — | US | claimed |
| EP-1868990-A2 | NOVEL HETEROCYCLIC DERIVATIVES | Orchid Research Laboratories Limited (IN) | 2007-12-26 | — | — | EP | claimed |
| WO-2006109146-A2 | NOVEL HETEROCYCLIC DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-10-19 | — | — | WO | claimed |
| US-20100305174-A1 | Novel Heterocyclic Derivatives | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305174-A1 | Novel Heterocyclic Derivatives | UGT1A1, CYP3A4, CYP3A43 | MMP3 3218/4885MMP13 3666/4885RAB9A 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.