Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | LPL | P06858 | 7/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.35 |
| ▸ | HTR1D | P28221 | 6/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197326 | 0.83 | BACE1 (0.38) | LPLLIPGPRMT5WDR77ROCK1 | |
| SCHEMBL3668225 | 0.83 | LIPG (0.36) | LPLLIPGPRMT5WDR77ROCK1 | |
| SCHEMBL16466430 | 0.81 | LIPG (0.41) | LPLLIPGPRMT5WDR77ROCK1 | |
| SCHEMBL18150899 | 0.81 | ACACB (0.36) | LPLLIPGPRMT5WDR77ROCK1 | |
| SCHEMBL20612398 | 0.79 | HTR2A (0.53) | HTR2CHTR2ALPLLIPGHTR1D | |
| SCHEMBL14016154 | 0.79 | HTR2C (0.50) | HTR2CHTR2AHTR1D | |
| SCHEMBL3664117 | 0.78 | CNR2 (0.36) | HTR2C | |
| SCHEMBL28868834 | 0.78 | LIPG (0.43) | LPLLIPGROCK1 | |
| SCHEMBL22559508 | 0.77 | FFAR1 (0.38) | LPLLIPGPRMT5WDR77ROCK1 | |
| SCHEMBL22585700 | 0.77 | ROCK1 (0.40) | LPLLIPGPRMT5WDR77ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231653-B1 | ANTIBACTERIAL CONDENSED THIAZOLES | BIOTA EUROPE LTD (GB) | 2013-04-03 | — | — | EP | disclosed |
| US-8299065-B2 | Antibacterial condensed thiazoles | BIOTA EUROPE LTD. (GB) | 2012-10-30 | — | — | US | disclosed |
| US-20100305067-A1 | ANTIBACTERIAL CONDENSED THIAZOLES | BIOTA EUROPE LTD (GB) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305067-A1 | ANTIBACTERIAL CONDENSED THIAZOLES | NEK6, NEK1, TXK | HTR2C 2331/4885HTR2A 3223/4885LPL 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.