Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352292 | 0.96 | CA12 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5476790 | 0.94 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8572647 | 0.92 | CA12 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11731007 | 0.85 | CYP1A2 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11701536 | 0.84 | CA12 (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1557949 | 0.81 | CA12 (0.42) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21536585 | 0.80 | ALDH1A1 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL65107 | 0.80 | CA12 (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23478555 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL13081038 | 0.80 | CA12 (0.36) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842638-B2 | Polymerisation catalyst | INEOS EUROPE LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842638-B2 | Polymerisation catalyst | INEOS EUROPE LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-20080200625-A1 | Polymerisation Catalyst | INEOS SALES (UK) LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| US-20080200625-A1 | Polymerisation Catalyst | INEOS SALES (UK) LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| EP-1765881-A1 | POLYMERISATION CATALYST | INEOS EUROPE LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006008438-A1 | POLYMERISATION CATALYST | INEOS EUROPE LIMITED (GB) | 2006-01-26 | — | — | WO | disclosed |