SCHEMBL376239

SCHEMBL376239

Fc1c(F)c(F)c(C(F)(F)Br)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL926486 0.96
SCHEMBL3959137 0.82
SCHEMBL12908777 0.82
SCHEMBL927742 0.80
SCHEMBL15388311 0.79
SCHEMBL6820203 0.74
SCHEMBL11878368 0.73
SCHEMBL7783594 0.69
SCHEMBL312356 0.69 SMN1; SMN2 (0.36)
Perfluorotoluene SCHEMBL308464 0.69 SMN1; SMN2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US claimed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US claimed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US claimed
CN-119012965-B Mass spectrometry method and system 巴塞尔儿童医院 2025-06-10 CN disclosed
CN-119012965-A Mass spectrometry method and system 巴塞尔儿童医院 2024-11-22 CN disclosed
EP-4139281-B1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES UNIV HEIDELBERG (DE) 2024-05-08 EP disclosed
CN-116234858-A Compositions and methods for reacting organosilicon compounds with silicon-based hydrides catalyzed by fluorinated arylborane Lewis acids 美国陶氏有机硅公司 2023-06-06 CN disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
CN-116134074-A Compositions and methods for silyl hydride reactions catalyzed by fluorinated arylborane lewis acids 美国陶氏有机硅公司 2023-05-16 CN disclosed
WO-2023077678-A1 SMALL MOLECULE COMPOUND TARGETING SRSF6 PROTEIN AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2023-05-11 WO disclosed
CN-115677577-A Small molecular compound targeting SRSF6 protein, and preparation method and application thereof 中国药科大学 2023-02-03 CN disclosed
US-5789172-A Methods of determining the structure of a compound encoded by identifiers having tags TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-08-04 US disclosed
WO-1998013437-A1 TROPODEGRADABLE BROMINE-CONTAINING HALOCARBON ADDITIVES TO DECREASE FLAMMABILITY OF REFRIGERANTS, FOAM BLOWING AGENTS, SOLVENTS, AEROSOL PROPELLANTS, AND STERILANTS THE UNIVERSITY OF NEW MEXICO (US) 1998-04-02 WO disclosed
US-5721099-A Complex combinatorial chemical libraries encoded with tags TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-02-24 US disclosed
EP-0755514-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-01-29 EP disclosed
US-5565324-A FOR IDENTIFICATION OF NON-OLIGOMERIC COMPOUND, USING SOLID SUPPORT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1996-10-15 US disclosed
WO-1995028640-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-10-26 WO disclosed
EP-0665897-A4 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS. UNIV COLUMBIA (US) 1995-09-27 EP disclosed
EP-0665897-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-08-09 EP disclosed
WO-1994008051-A1 COMPLEX COMBINATORIAL CHEMICAL LIBRARIES ENCODED WITH TAGS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1994-04-14 WO disclosed