SCHEMBL926486

SCHEMBL926486

Fc1c(F)c(C(F)(F)Br)c(F)c(F)c1C(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL376239 0.96
SCHEMBL12908777 0.85
SCHEMBL3959137 0.78
SCHEMBL6820203 0.77
SCHEMBL927742 0.77
SCHEMBL15388311 0.74
SCHEMBL10684716 0.72
SCHEMBL11878368 0.69
SCHEMBL12869598 0.67 CES2 (0.36)
SCHEMBL312355 0.67 SMN1; SMN2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868213-B2 1,4-bis(bromodifluoromethyl) tetrafluorobenzene and producing method thereof YUAN-SHIN MATERIALS TECHNOLOGY CORP (TW) 2011-01-11 US claimed
US-20090171130-A1 1, 4-bis (bromodifluoromethyl ) tetrafluorobenzene and producing method thereof CHUNG-SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY. ARMAMENTS BUREAU. M.N.D. (TW) 2009-07-02 US claimed
JP-5301984-B2 2013-09-25 JP disclosed
CN-101525270-B 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof YUANXIN TECHNOLOGY MATERIALS CO LTD 2012-05-23 CN disclosed
CN-101525270-B 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof YUANXIN TECHNOLOGY MATERIALS CO LTD 2012-05-23 CN disclosed
US-7868213-B2 1,4-bis(bromodifluoromethyl) tetrafluorobenzene and producing method thereof YUAN-SHIN MATERIALS TECHNOLOGY CORP (TW) 2011-01-11 US disclosed
US-7868213-B2 1,4-bis(bromodifluoromethyl) tetrafluorobenzene and producing method thereof YUAN-SHIN MATERIALS TECHNOLOGY CORP (TW) 2011-01-11 US disclosed
US-7868213-B2 1,4-bis(bromodifluoromethyl) tetrafluorobenzene and producing method thereof YUAN-SHIN MATERIALS TECHNOLOGY CORP (TW) 2011-01-11 US disclosed
CN-101525270-A 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof YUANXIN TECHNOLOGY MATERIALS C 2009-09-09 CN disclosed
CN-101525270-A 1, 4-bis (difluorobromomethyl) tetrafluorobenzene and preparation method thereof YUANXIN TECHNOLOGY MATERIALS C 2009-09-09 CN disclosed
JP-2009161530-A 1,4-BIS(BROMODIFLUOROMETHYL)TETRAFLUOROBENZENE AND METHOD FOR PRODUCING THE SAME YUAN-SHIN MATERIALS TECHNOLOGY CORP 2009-07-23 JP disclosed
US-20090171132-A1 METHOD FOR PRODUCING 1,4-BIS(DIFLUOROMETHYL)TETRAFLUOROBENZENE YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) 2009-07-02 US disclosed
US-7544846-B1 Method for producing 1,4-bis(difluoromethyl)tetrafluorobenzene YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) 2009-06-09 US disclosed
US-7544847-B1 Method for producing 1,4-bis (dichloromethyl) tetrafluorobenzene YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) 2009-06-09 US disclosed
US-7544847-B1 Method for producing 1,4-bis (dichloromethyl) tetrafluorobenzene YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) 2009-06-09 US disclosed
EP-0995734-B1 Method for production of halogen-containing aromatic compound NIPPON CATALYTIC CHEM IND (JP) 2004-05-12 EP disclosed
US-6433231-B2 BROMINATION THE CORRESPONDING NAPHTHALENE HALOGEN COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 2002-08-13 US disclosed
US-20010045350-A1 Method for production of halogen-containing aromatic compound NIPPON SHOKUBAI CO., LTD., A JAPAN CORPORATION 2001-11-29 US disclosed
US-6288290-B1 BROMINATION AND PHOTOBROMINATION OF AROMATIC COMPOUNDS NIPPON SHOKUBAI, CO., LTD. (JP) 2001-09-11 US disclosed
EP-0995734-A1 Method for production of halogen-containing aromatic compound Nippon Shokubai Co., Ltd. (JP) 2000-04-26 EP disclosed