Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.70 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330041 | 0.87 | IDO1 (0.72) | IDO1GPR84 | |
| SCHEMBL20168945 | 0.86 | IDO1 (0.59) | IDO1PDPK1GPR84 | |
| SCHEMBL14209228 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84 | |
| SCHEMBL21300294 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84 | |
| SCHEMBL20414390 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84RET | |
| SCHEMBL9391018 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84 | |
| SCHEMBL6419941 | 0.83 | IDO1 (1.00) | IDO1PDPK1CYP11B2GPR84RET | |
| SCHEMBL447419 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84RET | |
| SCHEMBL16392447 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84RET | |
| SCHEMBL447420 | 0.83 | IDO1 (0.66) | IDO1PDPK1CYP11B2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052530-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IE) | 2002-05-02 | — | — | US | claimed |
| US-6127579-A | REACTING AN INDANYL ETHER UNDER BASIC CONDITIONS TO GIVE A NOVEL SUBSTANCE WHICH IS THE INDENYL ETHER DERIVATIVE AND HYDROLYZING THIS TO GIVE THE 1-INDANONE | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-10-03 | — | — | US | claimed |
| EP-0968991-A1 | Method of manufacturing 1-indanone | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | claimed |
| EP-0874800-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | Venantius Limited (IE) | 1998-11-04 | — | — | EP | claimed |
| US-5733866-A | Methyl substituted hexahydroindanols and alkyl ethers thereof, organoleptic uses thereof, processes for preparing same and process intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1998-03-31 | — | — | US | claimed |
| WO-1997020805-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | claimed |
| CN-107690582-B | Apparatus and method for sample analysis | 雅培制药有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230302453-A1 | DEVICES AND METHODS FOR SAMPLE ANALYSIS | ABBOTT LABORATORIES (US) | 2023-09-28 | — | — | US | disclosed |
| CN-112892628-B | Apparatus and method for sample analysis | 雅培制药有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-11633738-B2 | Devices and methods for sample analysis | ABBOTT LABORATORIES (IL) | 2023-04-25 | — | — | US | disclosed |
| CN-113004293-B | Tetrahydrofuran [2,3-b ] indoline compound and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2023-03-14 | — | — | CN | disclosed |
| EP-3523640-B1 | DEVICES FOR SAMPLE ANALYSIS | ABBOTT LAB (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-113004294-B | Tetrahydrofuran-1, 4-dihydroquinoline compound and preparation method and application thereof | 温州大学新材料与产业技术研究院 | 2023-01-17 | — | — | CN | disclosed |
| US-5294730-A | A-Amino-4-alkoxy-3-polycycloalkyloxybenzyl cyanide derivatives | PFIZER INC. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0247725-B1 | Calcium independent camp phosphodiestrerase inhibitor antidepressant | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5196426-A | CALCIUM INDEPENDENT C AMP PHOSPHODIESTERASE INHIBITOR ANTIDEPRESSANT | PFIZER INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5128358-A | Aryl substituted nitrogen heterocyclic antidepressants | PFIZER INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0247725-A2 | Calcium independent camp phosphodiestrerase inhibitor antidepressant | PFIZER INC. (US) | 1987-12-02 | — | — | EP | disclosed |
| WO-1987006576-A1 | CALCIUM INDEPENDENT CAMP PHOSPHODIESTERASE INHIBITOR ANTIDEPRESSANT | PFIZER INC. (US) | 1987-11-05 | — | — | WO | disclosed |
| US-3850992-A | ALIPHATIC INDANYL ETHERS | SANDOZ | 1974-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052530-A1 | INDANE DIMER COMPOUNDS WITH SMOOTH MUSCLE RELAXING AND/OR MAST CELL STABILISING AND/OR ANTIINFLAMMATORY ACTIVITY | MYLK, HRH2, HRH1 | IDO1 43/4885PDPK1 3886/4885CYP11B2 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.