SCHEMBL37631

SCHEMBL37631

F[C](F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
LMNA P02545 1/20 0.40
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP13 P45452 1/20 0.33
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL815095 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL816969 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL713297 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL815182 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL735600 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL506161 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL392315 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL394581 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL64969 1.00 THRB (0.52) THRBLMNACA2CA1MMP1
SCHEMBL322581 1.00 THRB (0.52) THRBLMNACA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9800 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO claimed
CN-115708867-B Pulmonary administration oxygen-carrying nano-drug combined preparation for idiopathic pulmonary fibrosis and preparation method thereof 哈尔滨医科大学 2024-06-04 CN claimed
CN-118007407-A Long-acting super-hydrophobic fabric and preparation method thereof 罗莱生活科技股份有限公司 2024-05-10 CN claimed
CN-117603672-B Water-unlocking locking agent for low-permeability gas reservoir and preparation method thereof 中国石油大学(华东) 2024-05-07 CN claimed
CN-115181015-B Synthesis method of trisubstituted perfluoro alkylated ketene compound 温州大学 2024-04-26 CN claimed
WO-2024086390-A2 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-25 WO claimed
CN-117741837-A Flexible bending-resistant anti-reflection film and preparation method thereof 江苏斯迪克新材料科技股份有限公司 2024-03-22 CN claimed
CN-117603672-A Water-unlocking locking agent for low-permeability gas reservoir and preparation method thereof 中国石油大学(华东) 2024-02-27 CN claimed
CN-117247502-A Water-soluble antifouling acrylate monomer copolymer and preparation method and application thereof 怀化学院 2023-12-19 CN claimed
EP-4288496-A1 DIAMONDS COATINGS AND METHODS OF MAKING AND USING THE SAME Glisten LLC (US) 2023-12-13 EP claimed
US-5206440-A Oxidation of fluorine containing sulfides to sulfones E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-27 US claimed
US-5100569-A For use with Freon\" replacements such as 134a ALLIED-SIGNAL INC. (US) 1992-03-31 US claimed
US-5028516-A Method of forming an image comprising rapidly developing an infrared sensitized photographic material comprising surfactants FUJI PHOTO FILM CO., LTD. (JP) 1991-07-02 US claimed
EP-0252798-B1 AGENTS FOR PIGMENT CONCENTRATES BASED ON TELOMERS AND CONCENTRATES CONTAINING THE SAME TELOSUD (FR) 1990-09-12 EP claimed
US-4891306-A FLUOROPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1990-01-02 US claimed
EP-0338656-A2 Polymeric silicone-based materials with high oxygen permeability BAUSCH & LOMB INCORPORATED (US) 1989-10-25 EP claimed
US-4810764-A CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1989-03-07 US claimed
EP-0002004-B1 PROCESS FOR THE MANUFACTURE OF FLUORINATED CATIONIC COMPOUNDS AND THEIR USE AS SURFACTANTS CIBA-GEIGY AG (CH) 1982-03-24 EP claimed
EP-0002004-A1 Process for the manufacture of fluorinated cationic compounds and their use as surfactants CIBA-GEIGY AG (CH) 1979-05-30 EP claimed
US-3968137-A POLYMER INTERMEDIATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-06 US claimed