Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.76 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.76 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.76 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.76 |
| ▸ | TSPO | P30536 | 1/20 | 0.76 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CETP | P11597 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 3/20 | 0.60 |
| ▸ | GMNN | O75496 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561998 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL8736952 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL6055753 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL12766764 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL3885 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL17482409 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL3517452 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL22910837 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL20798182 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 | |
| SCHEMBL29380297 | 0.86 | S1PR1 (1.00) | S1PR1S1PR4S1PR3S1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190183910-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | OKTAY, KUTLUK (US) | 2019-06-20 | — | — | US | claimed |
| WO-2017223152-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | NEW YORK MEDICAL COLLEGE (US) | 2017-12-28 | — | — | WO | claimed |
| US-5877167-A | Method for inhibition of cell motility by sphingosine-1-phosphate and its derivatives | OTSUKA AMERICA PHARMACEUTICAL, INC. (US) | 1999-03-02 | — | — | US | claimed |
| EP-0671917-A4 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES. | BIOMEMBRANE INST (US) | 1997-06-18 | — | — | EP | claimed |
| EP-0671917-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | ONCOMEMBRANE, INC. (US) | 1995-09-20 | — | — | EP | claimed |
| US-5260288-A | Administering an inflammation inhibitory amount | THE BIOMEMBRANE INSTITUTE (US) | 1993-11-09 | — | — | US | claimed |
| WO-1993019760-A1 | METHOD FOR INHIBITION OF CELL MOTILITY BY SPHINGOSINE-1-PHOSPHATE, ITS DERIVATIVES AND MIMETICS AND METHOD OF SYNTHESIZING SPHINGOSINE-1-PHOSPHATE AND ITS DERIVATIVES | THE BIOMEMBRANE INSTITUTE (US) | 1993-10-14 | — | — | WO | claimed |
| US-20230152317-A1 | DIAGNOSIS AND TREATMENT OF COVID-19 | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2023-05-18 | — | — | US | disclosed |
| WO-2021207858-A1 | DIAGNOSIS AND TREATMENT OF COVID-19 | LONDON HEALTH SCIENCES CENTRE RESEARCH INC. (CA) | 2021-10-21 | — | — | WO | disclosed |
| US-20190183910-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | OKTAY, KUTLUK (US) | 2019-06-20 | — | — | US | disclosed |
| WO-2017223152-A1 | ENHANCING DNA REPAIR AND PREVENTING AGING AND ITS CONSEQUENCES IN REPRODUCTIVE AND OTHER CELLS | NEW YORK MEDICAL COLLEGE (US) | 2017-12-28 | — | — | WO | disclosed |
| US-7850984-B2 | Protection of the female reproductive system from natural and artificial insults | THE GENERAL HOSPITAL CORPORATION (US) | 2010-12-14 | — | — | US | disclosed |
| US-20070157331-A1 | Protection of female reproductive system from natural and artifical insults | MASSACHUSETTS GENERAL HOSPITAL, PARTNERS HEALTHCARE RESEARCH VENTURES & LICENSING (US) | 2007-07-05 | — | — | US | disclosed |
| EP-1257245-A2 | PROTECTION OF THE FEMALE REPRODUCTIVE SYSTEM FROM NATURAL AND ARTIFICIAL INSULTS | Sloan-Kettering Institute For Cancer Research (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060318-A2 | PROTECTION OF THE FEMALE REPRODUCTIVE SYSTEM FROM NATURAL AND ARTIFICIAL INSULTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2001-08-23 | — | — | WO | disclosed |
| US-5952152-A | POLYMERIZABLE MIXTURE COMPRISING AT LEAST ONE ETHYLENICALLY UNSATURATED COMPOUND AND AN ANIONIC BORON COMPOUND ACTIVATOR | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| US-5877167-A | Method for inhibition of cell motility by sphingosine-1-phosphate and its derivatives | OTSUKA AMERICA PHARMACEUTICAL, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5663404-A | ANTITUMOR AGENTS; ANTIINFLAMMATORY AGENTS | ONCOMEMBRANE (US) | 1997-09-02 | — | — | US | disclosed |
| US-5391800-A | Protecting hydroxyl groups of sphingosine, deprotecting C1, phosphorylating, deprotecting C3; free of L-threo isomer | THE BIOMEMBRANE INSTITUTE (US) | 1995-02-21 | — | — | US | disclosed |
| US-5260288-A | Administering an inflammation inhibitory amount | THE BIOMEMBRANE INSTITUTE (US) | 1993-11-09 | — | — | US | disclosed |