Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15296584 | 0.77 | CYP2A6 (0.38) | — | |
| SCHEMBL22337813 | 0.75 | — | — | |
| SCHEMBL25421716 | 0.75 | GAA (0.35) | — | |
| SCHEMBL24565969 | 0.75 | ACVR2A (0.35) | — | |
| SCHEMBL26117952 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL18949210 | 0.71 | NPC1 (0.31) | — | |
| SCHEMBL22337882 | 0.71 | SLC6A2 (0.30) | — | |
| SCHEMBL24569343 | 0.71 | SLC6A2 (0.30) | — | |
| SCHEMBL22607305 | 0.71 | SLC6A2 (0.30) | — | |
| SCHEMBL26751944 | 0.71 | SLC6A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015011400-A1 | NOVEL PYRROLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2015-01-29 | — | — | WO | disclosed |
| EP-2178375-A1 | PYRAZOLOÝ1,5-A¨PYRIMIDINE DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009014620-A1 | PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2009-01-29 | — | — | WO | disclosed |