Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21206874 | 0.92 | CALCRL (0.76) | CALCRLCYP3A4 | |
| SCHEMBL30231462 | 0.92 | CALCRL (0.81) | CALCRLCYP3A4 | |
| SCHEMBL3541678 | 0.92 | CALCRL (0.81) | CALCRLCYP3A4 | |
| SCHEMBL3541675 | 0.92 | CALCRL (0.81) | CALCRLCYP3A4 | |
| SCHEMBL18324492 | 0.90 | CALCRL (0.79) | CALCRLCYP3A4 | |
| SCHEMBL30231357 | 0.90 | CALCRL (0.79) | CALCRLCYP3A4 | |
| SCHEMBL3596473 | 0.90 | CALCRL (0.79) | CALCRLCYP3A4 | |
| SCHEMBL4813971 | 0.90 | CALCRL (0.79) | CALCRLCYP3A4 | |
| SCHEMBL3605480 | 0.90 | CALCRL (0.76) | CALCRLCYP3A4 | |
| SCHEMBL3597988 | 0.90 | CALCRL (0.78) | CALCRLCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842808-B2 | calcitonin gene-related peptide receptors antagonists such as 4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid[2-(1,4-dioxa-8-aza-spiro [4.5]dec-8-yl)-1-(1H-indol-5-ylmethyl)-2-oxo-ethyl]-amide, used for treating headaches, pain, hot flashes or respiratory system disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-11-30 | — | — | US | disclosed |
| US-20070149503-A1 | ANTI-MIGRAINE SPIROCYCLES | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149503-A1 | ANTI-MIGRAINE SPIROCYCLES | CALCRL, CALCR, CALCA | CALCRL 1/4885CYP3A4 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.