SCHEMBL3764689

SCHEMBL3764689

C=C(CC)C(=O)O.CCC=C(C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TET2 Q6N021 4/20 0.32
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
ALDH1A1 P00352 2/20 0.31
FFAR3 O14843 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9363617 1.00 ALOX15 (0.38) ALOX15HSD17B10TET2GRIK1GRIK2
SCHEMBL17763724 0.94 ALOX15 (0.34) ALOX15HSD17B10GRIK1GRIK2
Hydrochloric Acid SCHEMBL9525786 0.93 ALOX15 (0.33) ALOX15HSD17B10
Trimethylammonium SCHEMBL8832532 0.88 ALOX15 (0.31) ALOX15HSD17B10
SCHEMBL9293054 0.87 GRIK1 (0.36) ALOX15HSD17B10GRIK1GRIK2ALDH1A1
SCHEMBL9293058 0.87 GRIK1 (0.36) ALOX15HSD17B10GRIK1GRIK2ALDH1A1
Methacrylic Acid SCHEMBL8898658 0.85 GRIK1 (0.35) ALOX15HSD17B10GRIK1GRIK2TDP1
Methacrylic Acid SCHEMBL2023864 0.85 GRIK1 (0.35) ALOX15HSD17B10GRIK1GRIK2TDP1
Methacrylic Acid SCHEMBL8568777 0.85 GRIK1 (0.35) ALOX15HSD17B10GRIK1GRIK2TDP1
Methacrylic Acid SCHEMBL8898665 0.85 GRIK1 (0.35) ALOX15HSD17B10GRIK1GRIK2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009152144-A2 ALL DAY RHINITIC CONDITION TREATMENT REGIMEN CORNERSTONE THERAPEUTICS, INC. (US) 2009-12-17 WO claimed
US-20080311196-A1 All Day Rhinitic Condition Treatment Regimen CORNERSTONE BIOPHARMA, INC. 2008-12-18 US claimed
US-RE39239-E1 administering a time release dosage of a pharmaceutically active agent effective core surrounded by a coating of a swellable, erodable polymer; delivery of active agent at about the time of awakening POLICHEM SA (CH) 2006-08-15 US claimed
EP-0954292-A1 PHARMACEUTICAL FORMULATIONS WITH DELAYED DRUG RELEASE POLI INDUSTRIA CHIMICA S.p.A. (IT) 1999-11-10 EP claimed
US-5788987-A TIME-SPECIFIC CONTROLLED RELEASE DOSAGE FORMULATION POLI INDUSTRIA CHIMICA SPA (IT) 1998-08-04 US claimed
WO-1998032425-A1 PHARMACEUTICAL FORMULATIONS WITH DELAYED DRUG RELEASE POLI INDUSTRIA CHIMICA S.P.A. (US) 1998-07-30 WO claimed
US-20160206558-A1 GASTRIC RETENTIVE EXTENDED-RELEASE DOSAGE FORMS COMPRISING COMBINATIONS OF A NON-OPIOID ANALGESIC AND AN OPIOID ANALGESIC ASSERTIO THERAPEUTICS, INC. 2016-07-21 US disclosed
US-20140186440-A1 GASTRIC RETENTIVE EXTENDED-RELEASE DOSAGE FORMS COMPRISING COMBINATIONS OF A NON-OPIOID ANALGESIC AND AN OPIOID ANALGESIC DEPOMED, INC. (US) 2014-07-03 US disclosed
US-8668929-B2 Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic DEPOMED, INC. (US) 2014-03-11 US disclosed
US-8394408-B2 Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic DEPOMED, INC. (US) 2013-03-12 US disclosed
US-8372432-B2 Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic DEPOMED, INC. (US) 2013-02-12 US disclosed
US-20120321713-A1 GASTRIC RETENTIVE EXTENDED-RELEASE DOSAGE FORMS COMPRISING COMBINATIONS OF A NON-OPIOID ANALGESIC AND AN OPIOID ANALGESIC DEPOMED, INC. (US) 2012-12-20 US disclosed
US-20120136022-A1 GASTRIC RETENTIVE EXTENDED-RELEASE DOSAGE FORMS COMPRISING COMBINATIONS OF A NON-OPIOID ANALGESIC AND AN OPIOID ANALGESIC DEPOMED, INC. (US) 2012-05-31 US disclosed
US-20100196474-A1 Gastric Retentive Extended-Release Dosage Forms Comprising Combinations of a Non-Opioid Analgesic and an Opioid Analgesic DEPOMED, INC. (US) 2010-08-05 US disclosed
EP-0433871-B1 Screen-printable acrylate pressure-sensitive adhesive composition MINNESOTA MINING & MFG (US) 1994-11-02 EP disclosed
US-5141989-A Adhesion, shear strength, waterproof;(meth)acrylic ester, (meth)acrylic acid copolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-25 US disclosed
EP-0433871-A1 Screen-printable acrylate pressure-sensitive adhesive composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-26 EP disclosed