SCHEMBL3764945

SCHEMBL3764945

COC(=O)C=Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)nc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
MTOR P42345 2/20 0.50
ALDH1A1 P00352 2/20 0.50
THRB P10828 1/20 0.50
MDM2 Q00987 1/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
NFKB1 P19838 1/20 0.50
DNMT1 P26358 1/20 0.50
THPO P40225 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
BLM P54132 1/20 0.50
HBB P68871 1/20 0.50
PMP22 Q01453 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.45
POLB P06746 1/20 0.45
ADORA2A P29274 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11313283 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL3764941 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL3764936 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL2586211 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL11313278 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL18081847 1.00 LMNA (0.50) LMNAMTORALDH1A1THRBMDM2
SCHEMBL766492 0.91 ADORA2A (0.42) LMNAMTORALDH1A1THRBMDM2
SCHEMBL767826 0.91 ADORA2A (0.42) LMNAMTORALDH1A1THRBMDM2
SCHEMBL766491 0.91 ADORA2A (0.42) LMNAMTORALDH1A1THRBMDM2
SCHEMBL766490 0.91 ADORA2A (0.42) LMNAMTORALDH1A1THRBMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7842512-B2 Dyed microspheres for characterization of photochemical reactor behavior PURDUE RESEARCH FOUNDATION (US) 2010-11-30 US claimed
US-20060017008-A1 Dyed microspheres for characterization of photochemical reactor behavior PURDUE RESEARCH FOUNDATION 2006-01-26 US claimed
CN-118679180-A Polypeptides comprising D-domains and uses thereof 阿奇利克斯股份有限公司 2024-09-20 CN disclosed
CN-115160438-A Polypeptides comprising de novo binding domains and uses thereof 苏伯多曼有限责任公司 2022-10-11 CN disclosed
CN-105112503-B The method for screening binding interactions using particle and unique probes group 兰姆达公司 2018-10-16 CN disclosed
US-7842512-B2 Dyed microspheres for characterization of photochemical reactor behavior PURDUE RESEARCH FOUNDATION (US) 2010-11-30 US disclosed
US-20060017008-A1 Dyed microspheres for characterization of photochemical reactor behavior PURDUE RESEARCH FOUNDATION 2006-01-26 US disclosed
EP-0235301-B1 PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES TEIJIN LIMITED (JP) 1992-07-22 EP disclosed
US-4965350-A FLUORESCENT DETECTORS TEIJIN LIMITED (JP) 1990-10-23 US disclosed
EP-0235301-A1 PYRIDOPYRIMIDINE NUCLEOTIDE DERIVATIVES TEIJIN LIMITED (JP) 1987-09-09 EP disclosed
US-4267171-A C-5 Substituted cytosine nucleosides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-05-12 US disclosed