SCHEMBL3764978

SCHEMBL3764978

O=C(O)c1c(F)c(F)c(S(=O)(=O)c2c(F)c(F)c(C(=O)O)c(C(=O)O)c2F)c(F)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.37
CA2 P00918 6/20 0.37
CA12 O43570 4/20 0.37
CA7 P43166 4/20 0.37
CA13 Q8N1Q1 4/20 0.37
F2 P00734 3/20 0.35
PRSS1 P07477 3/20 0.35
PRSS2 P07478 3/20 0.35
PRSS3 P35030 3/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074393 0.76 CA1 (0.37) CA1CA2CA12CA7CA13
SCHEMBL336394 0.76 CES2 (0.43) CA1CA2CA12CA7MEN1
SCHEMBL1635048 0.76 CYP1A2 (0.38) CA1CA2CA12CA7MEN1
SCHEMBL29449985 0.76 CES2 (0.43) CA1CA2CA12CA7MEN1
SCHEMBL9405062 0.74 CA1 (0.40) CA1CA2CA12CA7CA13
SCHEMBL31155297 0.74 CA1 (0.36) CA1CA2CA12CA7CA13
SCHEMBL10454093 0.73 CES2 (0.42) CA1CA2CA12CA7MEN1
Fluoride SCHEMBL10713010 0.73 CES2 (0.42) CA1CA2CA12CA7MEN1
Ammonia Solution, Strong SCHEMBL10455117 0.73 CES2 (0.42) CA1CA2CA12CA7MEN1
Fluoride SCHEMBL6448131 0.73 CES2 (0.42) CA1CA2CA12CA7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090118460-A1 SOLUBLE AROMATIC RANDOM COPOLYIMIDE AND PROCESS FOR PREPARING SAME LAURENTIAN UNIVERSITY (CA) 2009-05-07 US claimed
EP-2191059-B1 COATED FIBER AND METHOD FOR MAKING THE COATED FIBER SABIC INNOVATIVE PLASTICS IP (NL) 2015-04-01 EP disclosed
EP-2191059-A2 COATED FIBER AND METHOD FOR MAKING THE COATED FIBER Sabic Innovative Plastics IP B.V. (NL) 2010-06-02 EP disclosed
US-20090118460-A1 SOLUBLE AROMATIC RANDOM COPOLYIMIDE AND PROCESS FOR PREPARING SAME LAURENTIAN UNIVERSITY (CA) 2009-05-07 US disclosed
WO-2009039353-A2 FIBER COATED WITH POLYAMIC ACID OR POLYETHERIMIDE AND METHOD FOR MAKING THE COATED FIBER SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-03-26 WO disclosed
US-20090075080-A1 COATED FIBER AND METHOD FOR MAKING THE COATED FIBER GENERAL ELECTRIC COMPANY (US) 2009-03-19 US disclosed
US-6115514-A FILM THICKNESS OF POLYIMIDE FILM FORMED BY THERMALLY IMIDIZING A POLYAMIC ACID IS SET AT NOT MORE THAN 20 MICROMETERS; HUMIDITY RESISTANCE, STRENGTH, FLEXIBILITY NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-09-05 US disclosed
US-6072920-A Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 2000-06-06 US disclosed
US-6048986-A DEHYDRATION OF DIFLUOROPYROMELLITIC ACID TO FORM DIFLUOROPYROMELLITIC DIANHYDRIDE NIPPON TELEGRAPH AND TELEPHONE CORP. (JP) 2000-04-11 US disclosed
EP-0623830-B1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH & TELEPHONE (JP) 1999-08-18 EP disclosed
EP-0480266-B1 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH & TELEPHONE (JP) 1996-06-26 EP disclosed
US-5449741-A Electronics with impact strength NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1995-09-12 US disclosed
EP-0623830-A1 Optical waveplate, method of manufacturing the same, and waveguide device using the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-11-09 EP disclosed
US-5233018-A Heat resistance and low optical transmission loss in the near-infrared region; integrated circuits NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1993-08-03 US disclosed
US-5112942-A Copolymers, aromatic diamine with alkyl substituents and phenoxy substituted aromatic diamine, resistance to stess cracking ETHYL CORPORATION (US) 1992-05-12 US disclosed
EP-0480266-A2 Perfluorinated polyimide, perfluorinated poly(amic acid), starting compounds therefor, and methods for preparing them NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-15 EP disclosed
US-4963649-A LOW GLASS TRANSITION TEMPERATURES; FOR HOT MELT ADHESIVES, PREPREGS ETHYL CORPORATION (US) 1990-10-16 US disclosed
US-4687836-A FROM 3,3*-DIAMINOBENZOPHENONE AND BENZOPHENONETETRACARBOXYLIC ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1987-08-18 US disclosed
EP-0179604-A2 Polyimide adhesives, coats and prepreg MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-04-30 EP disclosed
US-4124651-A Process for the production of polyamide-polyamide-acid copolymers CIBA-GEIGY CORPORATION (US) 1978-11-07 US disclosed