SCHEMBL3765623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3765617	1.00	ALDH1A1 (0.58)	ALDH1A1LMNATP53GPR183KMT2A
	SCHEMBL3765334	0.90	ALDH1A1 (0.47)	ALDH1A1LMNATP53GPR183KMT2A
	SCHEMBL3765327	0.90	ALDH1A1 (0.47)	ALDH1A1LMNATP53GPR183KMT2A
	SCHEMBL3767721	0.89	MEN1 (0.56)	GPR183KMT2AHRH3
	SCHEMBL3767727	0.89	MEN1 (0.56)	GPR183KMT2AHRH3
	SCHEMBL3773864	0.89	MEN1 (0.56)	ALDH1A1LMNAGPR183KMT2A
	SCHEMBL3773866	0.89	MEN1 (0.56)	ALDH1A1LMNAGPR183KMT2A
	SCHEMBL3762991	0.89	GPR183 (0.50)	ALDH1A1LMNATP53GPR183KMT2A
	SCHEMBL3762986	0.89	GPR183 (0.50)	ALDH1A1LMNATP53GPR183KMT2A
	SCHEMBL3761251	0.87	KDM4E (0.50)	ALDH1A1LMNAGPR183KMT2AHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.