Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514467 | 0.74 | BPTF (0.92) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL24858530 | 0.72 | BPTF (0.54) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL3762032 | 0.72 | ALDH1A1 (0.44) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL620749 | 0.71 | BPTF (1.00) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL3766049 | 0.70 | PIK3CA (0.46) | ALDH1A1MAPTHSD17B10MAPK1KMT2A | |
| SCHEMBL1719516 | 0.69 | ALDH1A1 (1.00) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL31381502 | 0.69 | BPTF (0.96) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL3492367 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MAPTGAAHSD17B10MAPK1 | |
| SCHEMBL2614831 | 0.68 | ALDH1A1 (1.00) | BPTFALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL5360384 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MAPTGAAHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| US-8324204-B2 | Fused thiophene derivatives as kinase inhibitors | UCB PHARMA SA (BE) | 2012-12-04 | — | — | US | disclosed |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-12-02 | — | — | US | disclosed |
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-0150319-B1 | COLOUR-PHOTOGRAPHIC RECORDING MATERIAL WITH A BLUE-GREEN DYE RELEASING COMPOUND, THE COLOUR IMAGE OBTAINED BY MEANS OF THIS DYE AND THE DYE ITSELF | Agfa-Gevaert AG (DE) | 1987-07-01 | — | — | EP | disclosed |
| US-4579805-A | DIFFUSION TRANSFER | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1986-04-01 | — | — | US | disclosed |
| EP-0150319-A2 | Colour-photographic recording material with a blue-green dye releasing compound, the colour image obtained by means of this dye and the dye itself | Agfa-Gevaert AG (DE) | 1985-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | PIKFYVE, PI4KA, PIK3CA | BPTF 2836/4885ALDH1A1 3061/4885MAPT 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.