SCHEMBL376597

SCHEMBL376597

O=C(Oc1c(F)cc(F)cc1F)C(=O)Oc1c(F)cc(F)cc1F

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.45
CES2 O00748 8/20 0.43
CES1 P23141 8/20 0.43
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
HCAR1 Q9BXC0 1/20 0.32
CA9 Q16790 2/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
LOX P28300 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27952466 0.89 ERN1 (0.41) ERN1CES2CES1GAAKMT2A
SCHEMBL5272075 0.85 CES2 (0.43) ERN1CES2CES1GAAKMT2A
SCHEMBL18697364 0.85 CES2 (0.43) ERN1CES2CES1GAAKMT2A
SCHEMBL19546521 0.83 CES2 (0.41) ERN1CES2CES1GAAKMT2A
SCHEMBL26770520 0.83 CES2 (0.41) ERN1CES2CES1GAAKMT2A
SCHEMBL28947411 0.81 CES2 (0.40) ERN1CES2CES1GAAKMT2A
SCHEMBL26770744 0.81 CES2 (0.40) ERN1CES2CES1GAAKMT2A
SCHEMBL5438858 0.81 CYP4F2 (0.47) ERN1CES2CES1GAAKMT2A
SCHEMBL15754940 0.79 CES2 (0.39) ERN1CES2CES1GAAKMT2A
SCHEMBL28443488 0.78 CES2 (0.38) ERN1CES2CES1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113614530-B Magnetic particles and detection reagent 积水医疗株式会社 2024-09-10 CN disclosed
CN-113646632-B Magnetic particles and detection reagent 积水医疗株式会社 2024-09-10 CN disclosed
EP-3796001-B1 METHOD FOR DETERMINING PROSTATE CARCINOMA FUJIFILM CORP (JP) 2023-08-09 EP disclosed
US-20230228769-A1 METHOD OF ASSISTING DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
EP-4187246-A1 METHOD FOR ASSISTING DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE FUJIFILM Corporation (JP) 2023-05-31 EP disclosed
US-11579146-B2 Detection of haptoglobin for gastrointestinal cancer determination FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-02-14 US disclosed
EP-4083624-A1 METHOD FOR ASSISTING DIAGNOSIS OF METASTATIC CASTRATION-RESISTANT PROSTATE CANCER FUJIFILM Corporation (JP) 2022-11-02 EP disclosed
US-20220326242-A1 METHOD OF ASSISTING DIAGNOSIS OF METASTATIC CASTRATION RESISTANT PROSTATE CANCER FUJIFILM CORPORATION (JP) 2022-10-13 US disclosed
CN-109313193-B Method for determining digestive tract cancer 富士胶片株式会社 2022-09-23 CN disclosed
CN-115004031-A Method for aiding diagnosis of metastatic androgen-blockade therapy resistant prostate cancer 富士胶片株式会社 2022-09-02 CN disclosed
US-5585248-A SPLITTING OF AN (OLIGO OR POLY)PEPTIDE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-12-17 US disclosed
US-5571729-A COMBINING ANALYTE/AFFINITY SUBSTANCE A COMPLEX WITH AN AFFINITY SUBSTANCE B AND SEPARATING COMPLEX COMBINED WITH SUBSTANCE B FROM FREE SUBSTANCE A WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-05 US disclosed
EP-0488755-B1 Process for rapid measurement of trace components WAKO PURE CHEM IND LTD (JP) 1996-06-26 EP disclosed
EP-0441470-B1 Process for separating and measuring trace components WAKO PURE CHEM IND LTD (JP) 1995-12-20 EP disclosed
EP-0657546-A1 Method for assaying activity of prophenoloxidase activating enzyme and application thereof Wako Pure Chemical Industries, Ltd. (JP) 1995-06-14 EP disclosed
EP-0653640-A1 Process for separating and measuring glycoprotein WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-05-17 EP disclosed
EP-0357869-B1 Affinity substance assay with HPLC step WAKO PURE CHEM IND LTD (JP) 1993-11-18 EP disclosed
EP-0488755-A1 Process for rapid measurement of trace components WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-06-03 EP disclosed
EP-0441470-A2 Process for separating and measuring trace components WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1991-08-14 EP disclosed
EP-0357869-A1 Affinity substance assay with HPLC step WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-03-14 EP disclosed