⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761108 | 1.00 | — | — | |
| SCHEMBL9442551 | 1.00 | — | — | |
| SCHEMBL7274806 | 0.82 | — | — | |
| SCHEMBL7274803 | 0.82 | — | — | |
| SCHEMBL7270024 | 0.82 | — | — | |
| SCHEMBL7269242 | 0.79 | ALOX5 (0.39) | — | |
| SCHEMBL5029010 | 0.79 | — | — | |
| SCHEMBL5369524 | 0.79 | — | — | |
| SCHEMBL10034950 | 0.79 | — | — | |
| SCHEMBL371100 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406043-A | Preparation method of 2, 5-bis- (2-furyl) pyrazine | 河北科技大学 | 2024-07-30 | — | — | CN | claimed |
| EP-0435840-A2 | Process for the preparation of 2-(2-furyl) ethanol amine | MONSANTO COMPANY (US) | 1991-07-03 | — | — | EP | claimed |
| US-4962212-A | Process for the preparation of 2-(2-furyl)ethanol amine | MONSANTO COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| EP-0005848-B1 | N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | claimed |
| JP-3197476-A | — | — | None | — | — | JP | disclosed |
| CN-118406043-A | Preparation method of 2, 5-bis- (2-furyl) pyrazine | 河北科技大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118406043-A | Preparation method of 2, 5-bis- (2-furyl) pyrazine | 河北科技大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-114989115-B | Improved synthesis of alpha- (nitromethyl) -2-furanmethanol and method for maintaining catalyst activity in the process | 兰升生物科技集团股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114989115-A | Improved synthesis of alpha- (nitromethyl) -2-furancarbinols and method for maintaining catalyst activity in such a process | 河北科技大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-112020490-A | Process for producing amines in solvent systems comprising water | 罗地亚经营管理公司 | 2020-12-01 | — | — | CN | disclosed |
| WO-2019174221-A1 | PROCESS FOR PRODUCING AN AMINE IN A SOLVENT SYSTEM CONTAINING WATER | RHODIA OPERATIONS (FR) | 2019-09-19 | — | — | WO | disclosed |
| US-10392715-B2 | Electrochemical reductive amination of furfural-based molecules | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-4962212-A | Process for the preparation of 2-(2-furyl)ethanol amine | MONSANTO COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0365045-A1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1990-04-25 | — | — | EP | disclosed |
| CN-1031375-A | The oxazolidine dihaloacetamides class of 5-heterocyclic substituted | MONSANTO CO (US) | 1989-03-01 | — | — | CN | disclosed |
| US-4699905-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0161801-A2 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
| US-4460580-A | N-Alkylated aminoalcohols and their pharmaceutical compositions useful for the treatment of cardiac insufficiency | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0005848-B1 | N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| EP-0005848-A1 | N-Alkylated aminoalcohols and their salts, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-12-12 | — | — | EP | disclosed |