SCHEMBL37668

SCHEMBL37668

Nc1c[nH]c2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.60
ATM Q13315 2/20 0.54
CYP3A4 P08684 2/20 0.52
GPR84 Q9NQS5 2/20 0.52
MEN1 O00255 2/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
AHR P35869 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
HTR2A P28223 4/20 0.50
HTR2C P28335 4/20 0.50
HTR6 P50406 2/20 0.50
CYP2A6 P11509 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MPO P05164 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR1D P28221 1/20 0.50
HTR1B P28222 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23704203 0.98 GFER (0.58) GFERATMCYP3A4GPR84MEN1
Iodide SCHEMBL2316312 0.98 GFER (0.58) GFERATMCYP3A4GPR84MEN1
SCHEMBL28110454 0.98 GFER (0.58) GFERATMCYP3A4GPR84MEN1
Bromide SCHEMBL28737265 0.98 GFER (0.58) GFERATMCYP3A4GPR84MEN1
Propane SCHEMBL28730352 0.91 GFER (0.53) GFERATMCYP3A4GPR84MEN1
SCHEMBL8079562 0.88 GFER (0.50) GFERATMCYP3A4GPR84MEN1
SCHEMBL28637564 0.82 GFER (0.49) GFERATMCYP3A4GPR84MEN1
SCHEMBL7300286 0.82 ATM (0.50) GFERATMCYP3A4GPR84MEN1
Trifluoroacetic Acid SCHEMBL30233736 0.82 MAPK1 (0.57) GFERATMGPR84MEN1MAPT
SCHEMBL31397676 0.76 GFER (1.00) GFERATMCYP3A4MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5835 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095084-A Antigen-specific T cell receptors and chimeric antigen receptors and methods of use in modulation of immune signaling for cancer immunotherapy 2026-05-26 CN claimed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US claimed
EP-4731758-A2 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY The Methodist Hospital (US) 2026-04-29 EP claimed
EP-4688823-A2 BIFUNCTIONAL MOLECULES TARGETING LYMPH NODE PROGENITOR EXHAUSTED T CELLS AND METHODS OF USE The Board of Trustees of the Leland Stanford Junior University (US) 2026-02-11 EP claimed
EP-4076482-B1 COMPOSITIONS FOR MODULATING GUT MICROFLORA POPULATIONS, ENHANCING DRUG POTENCY AND TREATING CANCER PERSEPHONE BIOSCIENCES INC (US) 2025-11-26 EP claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
US-12415988-B2 Enhanced differentiation of mesenchymal stem cells ESCAPE THERAPEUTICS, INC. 2025-09-16 US claimed
EP-3630807-B1 PD-1 AND CTLA-4 DUAL INHIBITOR PEPTIDES LEIDOS INC (US) 2025-08-13 EP claimed
EP-4594314-A1 PYRIDAZIN-3(2H)-ONE AND PYRIDIN-2(1H)-ONE PARP INHIBITOR COMPOUNDS Azkarra Therapeutics, Inc. (US) 2025-08-06 EP claimed
US-20250144151-A1 INTERACTION OF FIBROBLASTS AND IMMUNE CELLS FOR ACTIVATION AND USES THEREOF SPINALCYTE LLC (US) 2025-05-08 US claimed
WO-1991001756-A1 METHOD FOR CHEMICAL PROMOTION OF THE EFFECTS OF LOW CURRENT TRANSCRANIAL ELECTROSTIMULATION SKOLNICK MALCOLM H (US) 1991-02-21 WO claimed
EP-0224830-B1 GRAM NEGATIVE BACTERURIA TEST MILES INC. (US) 1991-01-16 EP claimed
EP-0360077-A2 Use of serotonin antagonists in the treatment of apoplexia cerebri Troponwerke GmbH & Co. KG (DE) 1990-03-28 EP claimed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 US claimed
US-4762781-A COUPLED TO AMINE OR GUANIDINE GROUPS OF HAPTENS VIA REACTION WITH DIALDEHYDE, IMMUNOLOGY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1988-08-09 US claimed
US-4717658-A URINARY TRACT INFECTIONS MILES INC. (US) 1988-01-05 US claimed
EP-0224830-A2 Gram negative bacteruria test MILES INC. (US) 1987-06-10 EP claimed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 EP claimed
EP-0149405-A2 Antibodies capable of specifically recognizing haptenic groups, their preparation and application, and antigens for the preparation of these antibodies Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1985-07-24 EP claimed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP claimed