Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37668 | 0.82 | GFER (0.60) | ATMALDH1A1TDP1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23704203 | 0.80 | GFER (0.58) | ATMALDH1A1TDP1KDM4ESMN1; SMN2 | |
| Iodide SCHEMBL2316312 | 0.80 | GFER (0.58) | ATMALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL28110454 | 0.80 | GFER (0.58) | ATMALDH1A1TDP1KDM4ESMN1; SMN2 | |
| Bromide SCHEMBL28737265 | 0.80 | GFER (0.58) | ATMALDH1A1TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL8079562 | 0.76 | GFER (0.50) | ATMALDH1A1TDP1GFERPRKD3 | |
| SCHEMBL20258216 | 0.75 | ATM (0.50) | ATMALDH1A1POLBTDP1KDM4E | |
| SCHEMBL17048751 | 0.75 | ATM (0.50) | ATMALDH1A1POLBTDP1KDM4E | |
| SCHEMBL1072588 | 0.75 | ATM (0.50) | ATMALDH1A1POLBTDP1KDM4E | |
| SCHEMBL2747487 | 0.75 | GPR84 (0.52) | ATMALDH1A1TDP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013061-A1 | 4(1H)QUINOLONE DERIVATIVES | LABORATORIOS ALMIRALL, SA (ES) | 1991-09-05 | — | — | WO | claimed |
| EP-0445062-A1 | 4(1H)Quinolone derivatives | LABORATORIOS ALMIRALL SA (ES) | 1991-09-04 | — | — | EP | claimed |
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
| WO-1991013061-A1 | 4(1H)QUINOLONE DERIVATIVES | LABORATORIOS ALMIRALL, SA (ES) | 1991-09-05 | — | — | WO | disclosed |
| EP-0445062-A1 | 4(1H)Quinolone derivatives | LABORATORIOS ALMIRALL SA (ES) | 1991-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | ATM 1727/4885ALDH1A1 144/4885POLB 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.