Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2075702 | 0.99 | KMT2A (0.32) | KMT2AMEN1 | |
| SCHEMBL3762462 | 0.92 | KMT2A (0.33) | KMT2AMEN1PDE9A | |
| Hydrochloric Acid SCHEMBL2077008 | 0.92 | KMT2A (0.33) | KMT2AMEN1PDE9A | |
| SCHEMBL3767477 | 0.91 | KMT2A (0.34) | KMT2AMEN1DGAT1PDE9A | |
| Hydrochloric Acid SCHEMBL2078367 | 0.90 | KMT2A (0.34) | KMT2AMEN1PDE9A | |
| SCHEMBL2076085 | 0.90 | KMT2A (0.37) | KMT2AMEN1DGAT1PDE9A | |
| SCHEMBL2078487 | 0.90 | CDK2 (0.34) | KMT2AMEN1DGAT1PDE9A | |
| SCHEMBL3773462 | 0.89 | NQO2 (0.34) | — | |
| SCHEMBL2078093 | 0.88 | DGAT1 (0.35) | KMT2AMEN1DGAT1 | |
| Hydrochloric Acid SCHEMBL2076120 | 0.88 | NQO2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024360-B1 | SUBSTITUTED PYRAZOLOPYRIMIDINES | CEPHALON INC (US) | 2013-04-03 | — | — | EP | claimed |
| US-7851468-B2 | Substituted pyrazolo[3,4-d]pyrimidines | CEPHALON, INC. (US) | 2010-12-14 | — | — | US | claimed |