SCHEMBL3767074

SCHEMBL3767074

C[Si](C)(Oc1cccc(N)c1)O[Si](C)(C)Oc1cccc(N)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
CYP3A4 P08684 3/20 0.55
TP53 P04637 1/20 0.50
MAOB P27338 2/20 0.48
TSHR P16473 1/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
APP P05067 1/20 0.39
MAP4K4 O95819 1/20 0.37
KMT2A Q03164 2/20 0.37
ATM Q13315 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30379190 1.00 ALDH1A1 (0.55) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL10884511 0.98 ALDH1A1 (0.53) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL1099831 0.92 ALDH1A1 (0.59) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL9260540 0.86 ALDH1A1 (0.59) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL10888520 0.86 CYP3A4 (0.42) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL10886069 0.84 CYP3A4 (0.41) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL8904993 0.83 ALDH1A1 (0.59) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL15375266 0.82 ALDH1A1 (0.63) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL10887836 0.81 NPSR1 (0.42) ALDH1A1CYP3A4TP53MAOBTSHR
SCHEMBL10887844 0.81 NPSR1 (0.42) ALDH1A1CYP3A4TP53MAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662378-B1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORP (JP) 2018-10-10 EP disclosed
US-9487726-B2 Imide compound, method for producing same, thickening agent for grease, and grease composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-11-08 US disclosed
US-20130345102-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-12-26 US disclosed
EP-2662378-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX Nippon Oil & Energy Corporation (JP) 2013-11-13 EP disclosed
US-7851121-B2 Photosensitive polyimide composition and polyimide precursor composition CENTRAL GLASS CO., LTD. (JP) 2010-12-14 US disclosed
US-20090176172-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION AND POLYIMIDE PRECURSOR COMPOSITION CENTRAL GLASS CO., LTD. (JP) 2009-07-09 US disclosed
US-4581461-A Maleated siloxane derivatives NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1986-04-08 US disclosed