SCHEMBL3767347

SCHEMBL3767347

COC(=O)c1ccc(C(=O)OC)c(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 15/20 0.62
ALDH1A1 P00352 10/20 0.62
HPGD P15428 5/20 0.62
HSD17B10 Q99714 5/20 0.62
MAPT P10636 4/20 0.62
ATM Q13315 3/20 0.62
GLA P06280 2/20 0.62
GAA P10253 2/20 0.62
CASP1 P29466 1/20 0.62
CASP7 P55210 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.54
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
XDH P47989 1/20 0.53
TSHR P16473 1/20 0.50
KMT2A Q03164 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967314 1.00 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL10400378 0.94 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL9080431 0.92 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL293610 0.92 KDM4E (0.53) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL13941280 0.91 POLB (0.58) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL126043 0.90 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL29492994 0.90 KDM4E (0.69) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL6339256 0.89 POLB (0.61) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL9697492 0.88 HSD17B10 (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL8013838 0.87 POLB (0.59) KDM4EALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101175785-B Hydrocarbon or hydrofluorocarbon blown ASTM E-84 class I rigid polyurethane foams BAYER MATERIALSCIENCE LLC 2011-02-09 CN claimed
CN-101175785-A Hydrocarbon or hydrofluorocarbon blown ASTM E-84 class i rigid polyurethane foams BAYER MATERIALSCIENCE LLC (US) 2008-05-07 CN claimed
US-5037862-A Excellent mechanical stability in printing HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-08-06 US claimed
CN-113412286-A Process for preparing polydienes having reduced cold flow properties 普利司通美国轮胎运营有限责任公司 2021-09-17 CN disclosed
EP-1480235-B1 FLEXIBLE MAGNET AND METHOD FOR MANUFACTURING MOTOR USING THE SAME PANASONIC CORP (JP) 2014-12-31 EP disclosed
CN-1962599-B Method for hydrogenating benzene polycarboxylic acids or derivatives thereof by using catalyst containing macropores BASF AG 2014-05-14 CN disclosed
US-7843045-B2 Thermoplastic resin composition for semiconductor, adhesion film, lead frame, and semiconductor device using the same, and method of producing semiconductor device HITACHI CHEMICAL CO., LTD. (JP) 2010-11-30 US disclosed
US-7560307-B2 Resin composition, heat-resistant resin paste and semiconductor device using these and method of preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-07-14 US disclosed
US-20090091012-A1 THERMOPLASTIC RESIN COMPOSITION FOR SEMICONDUCTOR, ADHESION FILM, LEAD FRAME, AND SEMICONDUCTOR DEVICE USING THE SAME, AND METHOD OF PRODUCING SEMICONDUCTOR DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-04-09 US disclosed
CN-100406428-C Process for hydrogenating benzenepolycarboxylic acids or derivatives thereof using catalysts containing macropores BASF AG (DE) 2008-07-30 CN disclosed
US-7381280-B2 Manufacturing methods of flexible bonded magnet and motor using the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-06-03 US disclosed
CN-1285815-A Process for hydrogenating benzenepolycarboxylic acids or derivatives thereof using catalysts containing macropores BASF AG (DE) 2001-02-28 CN disclosed
WO-1996034851-A1 BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed
US-5212279-A Hot-melt adhesive and its use in polyimide film and printed circuit board HITACHI CHEMICAL CO., LTD. (JP) 1993-05-18 US disclosed
US-5037862-A Excellent mechanical stability in printing HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-08-06 US disclosed
CN-1007492-B TECHNOLOGY FOR RECIRCULATING USE OF CATALYST IDEMITSU PETROCHEMICAL CO (JP) 1990-04-11 CN disclosed
CN-87104325-A Catalyst circulation is used technology 1988-07-06 CN disclosed
EP-0017422-B1 THERMOPLASTIC POLYAMIDEIMIDE COPOLYMERS AND METHOD OF PREPARATION TORAY INDUSTRIES, INC. (JP) 1983-11-30 EP disclosed
US-4299945-A HEAT POLYMERIZATION OF AN AROMATIC DIAMINO COMPOUND AND AN AROMATIC TRIBASIC CARBOXYLIC ACID TORAY INDUSTRIES, INC. (JP) 1981-11-10 US disclosed
EP-0017422-A1 Thermoplastic polyamideimide copolymers and method of preparation TORAY INDUSTRIES, INC. (JP) 1980-10-15 EP disclosed