Iodipamide

Iodipamide

SCHEMBL37678

O=C(CCCCC(=O)Nc1c(I)cc(I)c(C(=O)O)c1I)Nc1c(I)cc(I)c(C(=O)O)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 1.00
MAPK1 P28482 1/20 1.00
HDAC1 Q13547 14/20 0.41
HDAC6 Q9UBN7 14/20 0.41
HDAC11 Q96DB2 13/20 0.41
HDAC8 Q9BY41 13/20 0.41
HDAC4 P56524 12/20 0.41
HDAC7 Q8WUI4 12/20 0.41
HDAC9 Q9UKV0 12/20 0.41
HDAC5 Q9UQL6 12/20 0.41
HDAC3 O15379 12/20 0.41
HDAC2 Q92769 12/20 0.41
HDAC10 Q969S8 12/20 0.41
NCOR2 Q9Y618 2/20 0.38
KDM4E B2RXH2 1/20 0.38
BRD4 O60885 1/20 0.38
NCOR1 O75376 1/20 0.38
NR1I2 O75469 1/20 0.38
EGFR P00533 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodipamide SCHEMBL29606858 1.00 TSHR (1.00) TSHRMAPK1HDAC1HDAC6HDAC11
Iodipamide SCHEMBL1860819 0.98 TSHR (0.97) TSHRMAPK1HDAC1HDAC6HDAC11
Iodipamide SCHEMBL8816246 0.93 TSHR (0.86) TSHRMAPK1HDAC1HDAC6HDAC11
Iodipamide SCHEMBL10620456 0.92 TSHR (0.84) TSHRMAPK1HDAC1HDAC6HDAC11
SCHEMBL12143826 0.89 TSHR (0.80) TSHRMAPK1HDAC1HDAC6HDAC11
SCHEMBL29204744 0.88 MAPK1 (0.78) TSHRMAPK1HDAC1HDAC6HDAC11
SCHEMBL8212411 0.87 TSHR (0.76) TSHRMAPK1HDAC1HDAC6HDAC11
Iotranic Acid SCHEMBL2109613 0.85 TSHR (0.74) TSHRMAPK1CYP3A4MEN1POLB
Iodoxamic Acid SCHEMBL29397252 0.85 TSHR (0.74) TSHRMAPK1CYP3A4MEN1POLB
Iodoxamic Acid SCHEMBL377402 0.85 TSHR (0.74) TSHRMAPK1CYP3A4MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2396 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132404-A1 MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS ALNYLAM PHARMACEUTICALS, INC. (US) 2026-05-14 US claimed
EP-4561631-A2 MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS Alnylam Pharmaceuticals, Inc. (US) 2025-06-04 EP claimed
US-20250170280-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
US-20250170279-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
US-12269021-B2 Artificial protein catalyst GLYTECH, INC. (JP) 2025-04-08 US claimed
WO-2024176961-A1 PROTEIN RECOGNIZING K-Ras GENE MUTATION CANCER 国立研究開発法人理化学研究所 2024-08-29 WO claimed
WO-2024073709-A2 MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS ALNYLAM PHARMACEUTICALS, INC. (US) 2024-04-04 WO claimed
CN-115245411-A Adjustable vascular stent with different developing areas 张敏 2022-10-28 CN claimed
US-20220241765-A1 NOVEL ARTIFICIAL PROTEIN CATALYST GLYTECH, INC. (JP) 2022-08-04 US claimed
EP-3978023-A1 NOVEL ARTIFICIAL PROTEIN CATALYST Glytech, Inc. (JP) 2022-04-06 EP claimed
US-5264610-A X-ray contrast agents STERLING WINTHROP INC. (US) 1993-11-23 US claimed
US-5260478-A Contrast agents in x-ray imaging compositions; medical diagnosis STERLING WINTHROP INC. (US) 1993-11-09 US claimed
CN-1074378-A Radiophotography is with contrast agent and contrast compositions and utilize the radiological imaging method of this type of medicament GUERBET SA (FR) 1993-07-21 CN claimed
EP-0510086-A4 INTERDIGITATION-FUSION LIPOSOMES AND GELS 1993-03-17 EP claimed
EP-0510086-A1 INTERDIGITATION-FUSION LIPOSOMES AND GELS. LIPOSOME CO INC (US) 1992-10-28 EP claimed
EP-0498482-A2 X-ray contrast compositions useful in medical imaging NanoSystems L.L.C. (US) 1992-08-12 EP claimed
EP-0274467-B1 HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM GEHO, W., Blair (US) 1992-05-20 EP claimed
CN-1061155-A The preparation method of injection embolism medicament for birth control with reducibility ZHAO SHENGCAI (CN) 1992-05-20 CN claimed
WO-1991010422-A1 INTERDIGITATION-FUSION LIPOSOMES AND GELS THE LIPOSOME COMPANY, INC. (US) 1991-07-25 WO claimed
EP-0050457-A1 Radiopaque cyanoacrylate compositions BioNexus, Inc. (US) 1982-04-28 EP claimed