Iodoxamic Acid

Iodoxamic Acid

SCHEMBL377402

O=C(CCOCCOCCOCCOCCC(=O)Nc1c(I)cc(I)c(C(=O)O)c1I)Nc1c(I)cc(I)c(C(=O)O)c1I

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.74
MAPK1 P28482 1/20 0.74
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
POLB P06746 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12142383 1.00 TSHR (0.74) TSHRMAPK1LMNACYP1A2CYP3A4
Iotranic Acid SCHEMBL2109613 1.00 TSHR (0.74) TSHRMAPK1LMNACYP1A2CYP3A4
Iodoxamic Acid SCHEMBL29397252 1.00 TSHR (0.74) TSHRMAPK1LMNACYP1A2CYP3A4
Iotroxic Acid SCHEMBL27729545 0.89 TSHR (0.65) TSHRMAPK1LMNANPC1RAB9A
Iotetric Acid SCHEMBL37863 0.89 TSHR (0.65) TSHRMAPK1LMNANPC1RAB9A
Iotroxic Acid SCHEMBL38038 0.89 TSHR (0.65) TSHRMAPK1LMNANPC1RAB9A
Iotetric Acid SCHEMBL27748028 0.89 TSHR (0.65) TSHRMAPK1LMNANPC1RAB9A
Iodipamide SCHEMBL29606858 0.85 TSHR (1.00) TSHRMAPK1CYP3A4MEN1KMT2A
Iodipamide SCHEMBL37678 0.85 TSHR (1.00) TSHRMAPK1CYP3A4MEN1KMT2A
SCHEMBL12143826 0.84 TSHR (0.80) TSHRMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006073711-A2 USE OF A MATRIX COMPRISING A CONTRAST AGENT IN SOFT TISSUES KUROS BIOSURGERY AG (CH) 2006-07-13 WO claimed
US-12350375-B2 Method for obtaining efficient viral vector-based compositions for vaccination or gene therapy LEUKOCARE AG (DE) 2025-07-08 US disclosed
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives BRACCO IMAGING S.P.A. (IT) 2025-04-08 US disclosed
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING S.P.A. (IT) 2025-04-03 US disclosed
CN-119095823-A Process for preparing 2,4, 6-triiodophenol derivatives 伯拉考成像股份公司 2024-12-06 CN disclosed
WO-2023209165-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING SPA (IT) 2023-11-02 WO disclosed
US-20220325250-A1 METHOD FOR OBTAINING EFFICIENT COMPOSITIONS COMPRISING VIRAL VECTORS FOR VACCINATION OR GENE THERAPY LEUKOCARE AG (DE) 2022-10-13 US disclosed
CN-114929233-A Phosphodiesterase type V inhibitor compositions, methods of making them, and methods of using them 美国瑞根特有限公司 2022-08-19 CN disclosed
US-20220202717-A1 Novel Method for Obtaining Efficient Viral Vector-Based Compositions for Vaccination or Gene Therapy LEUKOCARE AG (DE) 2022-06-30 US disclosed
US-11166915-B2 Method for obtaining efficient viral vector-based compositions for vaccination or gene therapy LEUKOCARE AG (DE) 2021-11-09 US disclosed
EP-0968173-A1 PROCESS FOR THE PREPARATION OF IODINATED CONTRAST AGENTS AND INTERMEDIATES THEREFOR NYCOMED IMAGING AS (NO) 2000-01-05 EP disclosed
WO-1999018054-A1 PROCESS FOR THE CRYSTALLISATION OF STERICALLY HINDERED COMPOUNDS NYCOMED IMAGING AS (NO) 1999-04-15 WO disclosed
US-5824821-A EPOXIDATION OF ALLYLAMINO COMPOUND, HYDROLYSIS TO YIELD 2,3-DIHYDROXYPROPYLAMINO COMPOUNDS NYCOMED IMAGING AS (NO) 1998-10-20 US disclosed
WO-1998034905-A1 PROCESS FOR THE PREPARATION OF IODINATED CONTRAST AGENTS AND INTERMEDIATES THEREFOR NYCOMED IMAGING AS (NO) 1998-08-13 WO disclosed
EP-0828705-A1 IODINATION PROCESS NYCOMED IMAGING AS (NO) 1998-03-18 EP disclosed
US-5672335-A ADMINISTERING TO ENHANCE CONTRAST IN COMPUTER TOMOGRAPHY SCHERING AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed
WO-1996037461-A1 IODINATION PROCESS NYCOMED IMAGING A.S (NO) 1996-11-28 WO disclosed
US-5575905-A Iodination process NYCOMED IMAGING AS (NO) 1996-11-19 US disclosed
US-5250283-A Alpha-fluoro-N-trifluoroacetyliopanoic acid; nontoxic choleretic agent for X-ray imaging of the bile ducts MOLECULAR BIOSYSTEMS, INC. (US) 1993-10-05 US disclosed
US-5143715-A N-trifluoroacetyliopanoic acid; nontoxic, increased choleretic activity; radiology MOLECULAR BIOSYSTEMS, INC. (US) 1992-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES TPO, IPO4, CYP4F2 TSHR 15/4885MAPK1 1171/4885LMNA 4646/4885
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives TPO, IPO4, CYP4F2 TSHR 15/4885MAPK1 1171/4885LMNA 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.