Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144814 | 0.81 | SRC (0.50) | SRCNR1H4EP300MEN1KMT2A | |
| SCHEMBL15589760 | 0.81 | CYP19A1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22276997 | 0.79 | SRC (0.51) | SRCNR1H4EP300MEN1KMT2A | |
| SCHEMBL22276761 | 0.79 | SRC (0.58) | SRCNR1H4EP300MEN1KMT2A | |
| SCHEMBL22531104 | 0.79 | SRC (0.51) | SRCNR1H4MEN1KMT2ACASP3 | |
| SCHEMBL15590034 | 0.78 | ALOX5 (0.57) | SRCNR1H4ALOX5 | |
| SCHEMBL22530280 | 0.78 | SRC (0.53) | SRCNR1H4EP300MEN1KMT2A | |
| SCHEMBL22530335 | 0.78 | SRC (0.47) | SRCNR1H4EP300MEN1KMT2A | |
| SCHEMBL22276758 | 0.78 | CHEK1 (0.54) | SRCNR1H4MEN1KMT2ACASP3 | |
| SCHEMBL22530963 | 0.76 | SRC (0.48) | SRCNR1H4EP300MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679455-B2 | Radiolabelling methods | HAMMERSMITH IMANET LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| WO-2010007363-A2 | PREPARATION OF FLUORINE-LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |