Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678245 | 1.00 | KDM4E (0.53) | KDM4EMAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL3768960 | 0.81 | MAPT (0.53) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3681086 | 0.81 | MAPT (0.53) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3764031 | 0.80 | NPFFR1 (0.62) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3682013 | 0.80 | NPFFR1 (0.62) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3765182 | 0.77 | KDM4E (0.73) | KDM4EMAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL3765183 | 0.77 | KDM4E (0.73) | KDM4EMAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL17367500 | 0.73 | HPGD (0.46) | KDM4EMAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL3765667 | 0.72 | NPFFR1 (0.55) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3765671 | 0.72 | NPFFR1 (0.55) | KDM4EMAPK1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426540-B2 | Tridentate ligand compounds with imino furan units, method for manufacturing said compounds, and their use in the preparation of catalysts for the homopolymerisation and copolymerisation of ethylene and alpha-olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-04-23 | — | — | US | claimed |
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-12-09 | — | — | US | claimed |
| EP-2003125-A1 | NEW TRIDENTATE LIGAND COMPOUNDS WITH IMINO FURAN UNITS, METHOD FOR MANUFACTURING SAID COMPOUNDS, AND THEIR USE IN THE PREPARATION OF CATALYSTS FOR THE HOMOPOLYMERISATION AND COPOLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-17 | — | — | EP | claimed |
| US-8426540-B2 | Tridentate ligand compounds with imino furan units, method for manufacturing said compounds, and their use in the preparation of catalysts for the homopolymerisation and copolymerisation of ethylene and alpha-olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-04-23 | — | — | US | disclosed |
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-12-09 | — | — | US | disclosed |
| EP-2003125-A1 | NEW TRIDENTATE LIGAND COMPOUNDS WITH IMINO FURAN UNITS, METHOD FOR MANUFACTURING SAID COMPOUNDS, AND THEIR USE IN THE PREPARATION OF CATALYSTS FOR THE HOMOPOLYMERISATION AND COPOLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311930-A1 | New Tridentate Ligand Compounds with Imino Furan Units, Method for Manufacturing Said Compounds, and their use in the Preparation of Catalysts for the Homopolymerisation and Copolymerisation of Ethylene and Alpha-Olefins | FDFT1, ETFB, ETFA | KDM4E 3630/4885MAPK1 3886/4885HSD17B10 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.