⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435510 | 0.73 | CD81 (0.31) | — | |
| SCHEMBL3773379 | 0.72 | — | — | |
| SCHEMBL28522762 | 0.68 | — | — | |
| SCHEMBL9243501 | 0.63 | HCAR2 (0.35) | — | |
| SCHEMBL28359359 | 0.61 | — | — | |
| SCHEMBL702584 | 0.61 | GRIK1 (0.33) | — | |
| SCHEMBL3135250 | 0.61 | GRIK1 (0.33) | — | |
| SCHEMBL4040653 | 0.59 | GRIK1 (0.32) | — | |
| SCHEMBL2808090 | 0.59 | GRIK1 (0.32) | — | |
| SCHEMBL154216 | 0.59 | CD81 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310622-A1 | DRY EYE TREATMENT BY PUNCTA PLUGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| WO-2009079559-A1 | DRY EYE TREATMENT BY PUNCTA PLUGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-25 | — | — | WO | disclosed |