SCHEMBL435510

SCHEMBL435510

CC(=CC[Si]1(C)CCC(C)(C)O[Si]1(C)C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CD81 P60033 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28522762 0.74
SCHEMBL3769486 0.73
SCHEMBL9723647 0.69
SCHEMBL3118646 0.68 ALDH1A1 (0.37)
SCHEMBL28359359 0.63
SCHEMBL865425 0.60 CD81 (0.37) CD81
SCHEMBL4147849 0.59 CD81 (0.39) CD81
SCHEMBL2874822 0.59 CD81 (0.39) CD81
SCHEMBL866685 0.59 CD81 (0.43) CD81
SCHEMBL28307575 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101698-B2 Surface active prepolymers with both fluorine-containing groups and hydrophilic groups BAUSCH & LOMB INCORPORATED (US) 2012-01-24 US claimed
US-8071704-B2 Prepolymerizable surface active monomers with both fluorine-containing groups and hydrophilic groups BAUSCH & LOMB INCORPORATED (US) 2011-12-06 US claimed
US-20110172374-A1 NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH HEALTH HOLDCO LIMITED (IE) 2011-07-14 US claimed
EP-2162474-B1 NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH & LOMB (US) 2011-01-19 EP claimed
EP-2162474-A1 NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS Bausch & Lomb Incorporated (US) 2010-03-17 EP claimed
US-20090092655-A1 NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS SOLTA MEDICAL DUTCH HOLDINGS B.V. (NL) 2009-04-09 US claimed
WO-2009045886-A1 NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH & LOMB INCORPORATED (US) 2009-04-09 WO claimed
WO-2009005955-A1 NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH & LOMB INCORPORATED (US) 2009-01-08 WO claimed
WO-2009005954-A2 NOVEL POLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH & LOMB INCORPORATED (US) 2009-01-08 WO claimed
US-20090012249-A1 NOVEL SURFACE ACTIVE PREPOLYMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS BAUSCH HEALTH HOLDCO LIMITED (IE) 2009-01-08 US claimed
EP-0611367-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0611379-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0611380-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. BAUSCH & LOMB (US) 1994-08-24 EP claimed
EP-0603268-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS. BAUSCH & LOMB (US) 1994-06-29 EP claimed
EP-0603270-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR MAKING THEM BAUSCH & LOMB INCORPORATED (US) 1994-06-29 EP claimed
WO-1993009154-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009155-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
WO-1993005085-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS BAUSCH & LOMB INCORPORATED (US) 1993-03-18 WO claimed
WO-1993005098-A1 WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS BAUSCH & LOMB INCORPORATED (US) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092655-A1 NOVEL PREPOLYMERIZABLE SURFACE ACTIVE MONOMERS WITH BOTH FLUORINE-CONTAINING GROUPS AND HYDROPHILIC GROUPS NOTUM, ITK, MFAP1 CD81 3749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.