SCHEMBL3769573

SCHEMBL3769573

CCCCCc1cccc(S)c1CCCCC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 1/20 0.45
PTGS2 P35354 1/20 0.45
CYSLTR2 Q9NS75 5/20 0.43
CYSLTR1 Q9Y271 5/20 0.43
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARA Q07869 2/20 0.42
PPARG P37231 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
KCNH2 Q12809 2/20 0.41
TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517160 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8517192 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8516954 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8517066 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8517483 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8517004 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8518028 0.98 LIPG (0.49) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8674592 0.96 LIPG (0.47) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL8517572 0.94 LIPG (0.39) LIPGALOX5PTGS2CYSLTR2CYSLTR1
SCHEMBL11210360 0.90 LIPG (0.38) LIPGALOX5PTGS2CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501840-B1 BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM SYMYX SOLUTIONS INC (US) 2010-12-22 EP disclosed
US-7659415-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX SOLUTIONS, INC. (US) 2010-02-09 US disclosed
US-20080269470-A1 Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom SYMYX TECHNOLOGIES, INC. (US) 2008-10-30 US disclosed
US-7241715-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 US disclosed
US-7126031-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2006-10-24 US disclosed
US-20060211892-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2006-09-21 US disclosed
US-7030256-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2006-04-18 US disclosed
US-20050164872-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. 2005-07-28 US disclosed
US-6897276-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2005-05-24 US disclosed
US-20050080281-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. 2005-04-14 US disclosed
US-6869904-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2005-03-22 US disclosed
EP-1501840-A1 BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS AND PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM Symyx Technologies, Inc. (US) 2005-02-02 EP disclosed
US-6841502-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2005-01-11 US disclosed
US-20040014950-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2004-01-22 US disclosed
US-20040010103-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. 2004-01-15 US disclosed
US-20040005984-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. 2004-01-08 US disclosed
WO-2003091262-A1 BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS AND PROCESSES FOR POLYMERIZING AND POYMERS THEREFROM SYMYX TECHNOLOGIES, INC. (US) 2003-11-06 WO disclosed
EP-0896050-A1 Lubricating oil composition comprising a specific base oil and an oxidation inhibitor NIPPON OIL CO., LTD. (JP) 1999-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014950-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom WEE1, WASF2, WEE2 LIPG 3329/4885ALOX5 164/4885PTGS2 1075/4885
US-20080269470-A1 Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom WEE1, WASF2, WEE2 LIPG 3329/4885ALOX5 164/4885PTGS2 1075/4885
US-20060211892-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom WEE1, WASF2, WEE2 LIPG 3329/4885ALOX5 164/4885PTGS2 1075/4885
US-20050164872-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom WEE1, WASF2, WEE2 LIPG 3017/4885ALOX5 169/4885PTGS2 1294/4885
US-20050080281-A1 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom WEE1, WASF2, WEE2 LIPG 3329/4885ALOX5 164/4885PTGS2 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.