Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772075 | 0.91 | FAAH (0.62) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3761321 | 0.90 | FAAH (0.74) | FAAHRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3772038 | 0.90 | FAAH (0.68) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3766248 | 0.89 | FAAH (0.61) | FAAHRAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL3772454 | 0.89 | FAAH (0.75) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3763272 | 0.88 | MAPT (0.72) | FAAHALDH1A1HSD17B10MAPTHTT | |
| SCHEMBL3771228 | 0.87 | FAAH (0.76) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3771739 | 0.87 | FAAH (0.60) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3770539 | 0.87 | FAAH (0.60) | FAAHRAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL3765717 | 0.87 | FAAH (0.60) | FAAHRAB9ANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |