SCHEMBL3770538

SCHEMBL3770538

CCCCN1C(=O)c2cccc3c(OCC)ccc(c23)C1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
POLB P06746 4/20 0.60
MAPT P10636 3/20 0.60
MAPK1 P28482 2/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
USP2 O75604 2/20 0.60
HTT P42858 2/20 0.60
ATM Q13315 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
TLR9 Q9NR96 2/20 0.60
RGS12 O14924 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
PRMT1 Q99873 1/20 0.51
CYP1B1 Q16678 5/20 0.49
ALDH1A1 P00352 4/20 0.49
LMNA P02545 4/20 0.49
KDM4E B2RXH2 3/20 0.49
PABPC1 P11940 3/20 0.49
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9437177 0.92 KMT2A (0.57) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL9437170 0.88 PRMT1 (0.68) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL30534976 0.88 PRMT1 (0.68) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL22829698 0.88 KMT2A (0.56) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL13751101 0.88 KMT2A (0.56) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL9437179 0.86 CYP1B1 (0.62) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL9437198 0.85 PRMT1 (0.70) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL14434610 0.84 KMT2A (0.52) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL14434650 0.83 KMT2A (0.51) KMT2AMEN1POLBMAPTMAPK1
SCHEMBL28167183 0.83 MEN1 (0.51) KMT2AMEN1POLBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833784-B2 Thermoplastic film and laminated glass SEKISUI CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11801667-B2 Thermoplastic film and laminated glass SEKISUI CHEMICAL CO., LTD. (JP) 2023-10-31 US disclosed
US-20220161523-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-26 US disclosed
US-20220154914-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
US-20220152992-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
EP-3943288-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
EP-3943295-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
EP-3943289-A1 THERMOPLASTIC FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-01-26 EP disclosed
CN-113573889-A Thermoplastic film and laminated glass 积水化学工业株式会社 2021-10-29 CN disclosed
CN-113573890-A Thermoplastic film and laminated glass 积水化学工业株式会社 2021-10-29 CN disclosed
US-8894881-B2 1,8-naphthalimide derivatives as scintillation agents, in particular for discriminating between fast neutrons and gamma rays COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-11-25 US disclosed
EP-2238112-B1 DERIVATIVES OF 1,8-NAPHTHALIMIDE AS SCINTILLATION AGENTS, ESPECIALLY FOR THE DISCRIMINATION BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2013-07-31 EP disclosed
EP-2238112-B1 DERIVATIVES OF 1,8-NAPHTHALIMIDE AS SCINTILLATION AGENTS, ESPECIALLY FOR THE DISCRIMINATION BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2013-07-31 EP disclosed
US-20100314556-A1 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2010-12-16 US disclosed
US-20100314556-A1 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2010-12-16 US disclosed
US-20100314556-A1 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2010-12-16 US disclosed
WO-2009095376-A1 DERIVATIVES OF 1,8-NAPHTHALIMIDE AS SCINTILLATION AGENTS, ESPECIALLY FOR THE DISCRIMINATION BETWEEN FAST NEUTRONS AND GAMMA RAYS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-08-06 WO disclosed
EP-0398764-B1 An organic thin-film el device NEC CORP (JP) 1994-10-19 EP disclosed
US-5093691-A ORGANIC THIN-FILM EL DEVICE NEC CORPORATION (JP) 1992-03-03 US disclosed
EP-0398764-A2 An organic thin-film el device NEC CORPORATION (JP) 1990-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100314556-A1 1,8-NAPHTHALIMIDE DERIVATIVES AS SCINTILLATION AGENTS, IN PARTICULAR FOR DISCRIMINATING BETWEEN FAST NEUTRONS AND GAMMA RAYS NPM1, NDC1, KPNB1 KMT2A 3994/4885MEN1 256/4885POLB 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.