KPNB1

Importin subunit beta-1 · Q14974 · KPNB1 on Sugi Atlas →

0 patent compounds predicted against KPNB1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to KPNB1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection PHASE3COMPLETED
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Efficacy of Ivermectin in COVID-19 PHASE1/PHASE2COMPLETED
Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma PHASE1/PHASE2RECRUITING
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel PHASE1COMPLETED
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion nanRECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China nanCOMPLETED
Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C nanRECRUITING
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction nanCOMPLETED
Biomarker for Niemann Pick Type C Disease (BioNPC) nanWITHDRAWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
A Study on the Prevalence of Mutation of Cerebrotendinous Xanthomatosis (CTX) nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Finding Genes With NGS Techniques in Whom Mutations Cause Neurological Diseases nanUNKNOWN
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Chordoma Family Study nanCOMPLETED
Plasma Triglyceride Lipolysis in Multifactorial Chylomicronemia nanCOMPLETED
Mackenzie's Mission: The Australian Reproductive Carrier Screening Project nanCOMPLETED
Induced Pluripotent Stem Cells for Niemann Pick Disease nanCOMPLETED
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a KPNB1 binder may also engage these)

ProteinNameSimilarity
P70168 1.000 P70168 →
P52296 1.000 P52296 →
P52297 0.992 P52297 →
TNPO1 Transportin-1 0.970 landscape →
Q8BFY9 0.968 Q8BFY9 →
Q3SYU7 0.967 Q3SYU7 →
O14787 0.966 O14787 →
XPO1 Exportin-1 0.960 landscape →
Q99LG2 0.959 Q99LG2 →
Q80U96 0.957 Q80U96 →
Q6P5F9 0.956 Q6P5F9 →
Q6IQT4 0.955 Q6IQT4 →
COPS2 COP9 signalosome complex subunit 2 0.954 landscape →
P61202 0.954 P61202 →
P61203 0.953 P61203 →
Q6IR75 0.953 Q6IR75 →
P79101 0.940 P79101 →
Q27HV0 0.940 Q27HV0 →
OGT UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 0.939 landscape →
Q9UKF6 0.939 Q9UKF6 →
P56558 0.939 P56558 →
Q9QXK7 0.938 Q9QXK7 →
P17427 0.938 P17427 →
P18484 0.937 P18484 →
Q8CGY8 0.936 Q8CGY8 →
P81436 0.935 P81436 →
Q5R8K2 0.934 Q5R8K2 →
Q99LD4 0.933 Q99LD4 →
Q99LC2 0.933 Q99LC2 →
Q5BJQ6 0.933 Q5BJQ6 →