Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718144 | 0.87 | LMNA (0.50) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL11148803 | 0.87 | LMNA (0.50) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL14462419 | 0.87 | LMNA (0.50) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL9174807 | 0.85 | LMNA (0.55) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL14462730 | 0.84 | LMNA (0.53) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL27989118 | 0.83 | LMNA (0.42) | LMNAFFAR4ACACBACACAFFAR1 | |
| SCHEMBL904359 | 0.81 | FFAR1 (0.55) | LMNAFFAR4FFAR1GPR84FAAH | |
| SCHEMBL5678381 | 0.81 | FFAR1 (0.55) | LMNAFFAR4FFAR1GPR84FAAH | |
| SCHEMBL1543206 | 0.81 | FFAR1 (0.55) | LMNAFFAR4FFAR1GPR84FAAH | |
| SCHEMBL8921629 | 0.81 | FFAR1 (0.55) | LMNAFFAR4FFAR1GPR84FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311700-A1 | Transdermal preparation for external use containing nonsterioidal antiinflammatory/analgesic agent | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20080317689-A1 | Transdermal Preparation for External Use Containing Antiinflammatory/Analgesic Agent | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2008-12-25 | — | — | US | disclosed |