SCHEMBL3770673

SCHEMBL3770673

CC=CCCCCCOc1cccc(CN)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
LTB4R Q15722 3/20 0.34
LTB4R2 Q9NPC1 2/20 0.34
RPS6KA1 Q15418 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MCHR1 Q99705 1/20 0.32
NCF1 P14598 1/20 0.32
HTR1B P28222 1/20 0.32
CYP3A4 P08684 2/20 0.31
MEN1 O00255 1/20 0.31
NR1I2 O75469 1/20 0.31
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3766281 0.99 L3MBTL1 (0.36) L3MBTL1TDP1MAPTALDH1A1MAPK1
SCHEMBL3770868 0.94 L3MBTL1 (0.36) L3MBTL1TDP1MAPTALDH1A1MAPK1
SCHEMBL3764835 0.90 RPS6KA1 (0.35) L3MBTL1TDP1MAPTALDH1A1MAPK1
SCHEMBL3770876 0.86 L3MBTL1 (0.38) L3MBTL1TDP1MAPTLTB4RLTB4R2
SCHEMBL3759944 0.83 KDM4E (0.38) L3MBTL1TDP1MAPTALDH1A1RPS6KA1
SCHEMBL3766502 0.83 KDM4E (0.38) L3MBTL1TDP1MAPTALDH1A1RPS6KA1
SCHEMBL3771934 0.82 L3MBTL1 (0.39) L3MBTL1TDP1MAPTMAPK1RPS6KA1
SCHEMBL3766396 0.82 L3MBTL1 (0.39) L3MBTL1TDP1MAPTRPS6KA1HPGD
SCHEMBL3763009 0.81 KDM4E (0.39) L3MBTL1TDP1MAPTALDH1A1RPS6KA1
SCHEMBL3764641 0.81 TAAR1 (0.39) L3MBTL1MAPTRPS6KA1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 L3MBTL1 40/4885TDP1 4310/4885MAPT 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.