SCHEMBL377276

SCHEMBL377276

CCC(c1ccncc1)c1ccncc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 3/20 0.63
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
S1PR1 P21453 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123538 0.93 SLC6A3 (0.61) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL5999712 0.91 SLC6A3 (0.59) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL5999950 0.87 CYP17A1 (0.57) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL5999692 0.85 CYP19A1 (0.59) CYP17A1SLC6A2SLC6A4SLC6A3CYP19A1
Ammonia Solution, Strong SCHEMBL5999953 0.85 CYP17A1 (0.56) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL6000438 0.85 CYP17A1 (0.56) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL5999961 0.82 CYP17A1 (0.54) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL6000107 0.82 CYP17A1 (0.87) CYP17A1CYP3A4CYP2C19ALDH1A1LMNA
Ammonia Solution, Strong SCHEMBL5999965 0.82 CYP17A1 (0.49) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1
Ammonia Solution, Strong SCHEMBL6000329 0.80 CYP17A1 (0.58) CYP17A1SLC6A2SLC6A4SLC6A3S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104788501-B 4- methylphthalic acids and (4- pyridines) the propane mixture cobalt complexes of 1,3- bis- and preparation method 洛阳师范学院 2018-07-17 CN claimed
CN-107417928-A A kind of metallic silver coordination polymer containing mixed ligand and preparation method thereof 齐鲁工业大学 2017-12-01 CN claimed
CN-104624160-B Preparation method of thermal conduction enhanced metal organic framework gas storage material 北京科技大学 2017-01-25 CN claimed
CN-105315302-A Non-hydrous 1,3-di(4-pyridyl) propane copper o-chloromandelate ferroelectric functional material and preparation method therefor UNIV NINGBO 2016-02-10 CN claimed
CN-105085554-A 4-methyl phthalic acid and 1,3-two(4-pyridine) propane mixed silver complex and preparing method and application thereof UNIV LUOYANG NORMAL 2015-11-25 CN claimed
EP-2691123-A1 ETHYLENE OXIDE STERILIZATION INDICATOR COMPOSITIONS Illinois Tool Works, Inc. (US) 2014-02-05 EP claimed
WO-2012135628-A1 ETHYLENE OXIDE STERILIZATION INDICATOR COMPOSITIONS ILLINOIS TOOL WORKS INC. (US) 2012-10-04 WO claimed
EP-2173721-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
EP-2173747-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES Sanofi-Aventis (FR) 2010-04-14 EP claimed
WO-2009000413-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI-AVENTIS (FR) 2008-12-31 WO claimed
WO-2009000412-A1 A REGIOSELECTIVE METAL CATALYZED SYNTHESIS OF ANNELATED BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI AVENTIS (FR) 2008-12-31 WO claimed
US-6921824-B1 Ruthenium dimeric complexes suitable as antimetastatic and antineoplastic agents SIGEA S.R.L. (IT) 2005-07-26 US claimed
EP-1185540-B1 RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS SIGEA SRL (IT) 2003-08-27 EP claimed
EP-1185540-A1 RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS Sigea S.r.l. (IT) 2002-03-13 EP claimed
WO-2000063218-A1 RUTHENIUM DIMERIC COMPLEXES SUITABLE AS ANTIMETASTATIC AND ANTINEOPLASTIC AGENTS SIGEA S.R.L. (IT) 2000-10-26 WO claimed
EP-0484622-B1 Electrolytic solution for Karl Fischer's coulometric titration and method for measuring water content using same MITSUBISHI CHEM CORP (JP) 1996-12-27 EP claimed
EP-3380227-A1 PROCESS FOR PREPARATION OF A MOLDING COMPOSITION AND PRODUCTION OF SHAPED BODIES BASF SE (DE) 2018-10-03 EP disclosed
CN-104788501-B 4- methylphthalic acids and (4- pyridines) the propane mixture cobalt complexes of 1,3- bis- and preparation method 洛阳师范学院 2018-07-17 CN disclosed
WO-2009000413-A1 A REGIOSELECTIVE COPPER CATALYZED SYNTHESIS OF BENZIMIDAZOLES AND AZABENZIMIDAZOLES SANOFI-AVENTIS (FR) 2008-12-31 WO disclosed
EP-1990090-A1 MICROCHANNEL REACTOR Inter-University Research Institute Corporation National Institutes of Natural Sciences (JP) 2008-11-12 EP disclosed