SCHEMBL377304

SCHEMBL377304

C[C@]12CC[C@H]3[C@@H](CCC4CCCC[C@@]43C)[C@@H]1CC[C@@H]2C1=CC(=O)OC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 2/20 0.64
ATP1B1 P05026 2/20 0.64
ATP1A3 P13637 2/20 0.64
ATP1B2 P14415 2/20 0.64
ATP1A2 P50993 2/20 0.64
ATP1B3 P54709 2/20 0.64
FXYD2 P54710 2/20 0.64
ATP1A4 Q13733 2/20 0.64
CYP19A1 P11511 2/20 0.50
TP53 P04637 5/20 0.49
PAX8 Q06710 3/20 0.49
RAB9A P51151 3/20 0.49
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HIF1A Q16665 2/20 0.49
NPC1 O15118 2/20 0.49
CYP3A4 P08684 2/20 0.49
TSHR P16473 1/20 0.49
ATP12A P54707 1/20 0.49
HSD17B10 Q99714 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7389878 1.00 ATP1A1 (0.64) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL7389882 1.00 ATP1A1 (0.64) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL10638013 1.00 ATP1A1 (0.64) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL1649319 1.00 ATP1A1 (0.64) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL642564 0.99 ATP1A1 (0.63) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Phosphoric Acid SCHEMBL7997964 0.95 ATP1A1 (0.62) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL11566351 0.87 ATP1A1 (0.51) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL11211273 0.86 ATP1A1 (0.53) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
Dextrose SCHEMBL11214382 0.86 ATP1A1 (0.53) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL11212478 0.86 ATP1A1 (0.52) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102542-A1 ATPASE INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND NON-NEUROLOGICAL DISORDERS HAPLO THERAPEUTICS INC. (CA) 2026-05-21 WO claimed
WO-2026106785-A1 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES AND METHODS OF USE THEREOF BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) 2026-05-21 WO claimed
WO-2025215232-A1 A COMPOSITION COMPRISING A SAPONIN AND/OR AN ANTHELMINTIC AND/OR A MITOCHONDRIAL UNCOUPLER FOR THE TREATMENT OF LIVER DISEASE RAINCASTLE BIO. LIMITED (GB) 2025-10-16 WO claimed
US-12306185-B2 Detection of anti-p53 antibodies ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2025-05-20 US claimed
WO-2025093735-A2 AGENTS FOR USE IN THE TREATMENT OF TAUOPATHIES DRUG TARGET IP B.V. (NL) 2025-05-08 WO claimed
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-04-24 US claimed
EP-4490187-A2 EPO RECEPTOR AGONISTS AND ANTAGONISTS Immunedge, Inc. (US) 2025-01-15 EP claimed
WO-2024259191-A2 METHOD AND COMPOSITIONS FOR TREATING SKIN DISORDERS PHOENIX BIOTECHNOLOGY, INC. (US) 2024-12-19 WO claimed
US-12134787-B2 Method for increasing the yield of oxidosqualene, triterpenes and/or triterpenoids and host cell therefore FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2024-11-05 US claimed
US-20240272154-A1 DETECTION OF ANTI-p53 ANTIBODIES ROCHE DIAGNOSTICS OPERATIONS, INC. 2024-08-15 US claimed
US-4331802-A Organometallic reagents and their use in the synthesis of cardenolides and isocardenolides ADVANCE BIOFACTURES CORPORATION (US) 1982-05-25 US claimed
EP-0027023-A1 Furyl intermediates of cardenolides, their synthesis and production of cardenolides and their isomers therefrom Advance Biofactures Corporation (US) 1981-04-15 EP claimed
US-4259240-A Synthesis of furyl intermediates, and cardenolides and their isomers prepared therefrom ADVANCE BIOFACTURES CORPORATION (US) 1981-03-31 US claimed
US-4219549-A CARDIOTONIC AGENTS ETABLISSEMENTS NATIVELLE S.A. (FR) 1980-08-26 US claimed
US-4217280-A Amino-3-cardenolide derivatives, process for their preparation, and pharmaceutical compositions containing same ETABLISSEMENTS NATIVELLE S.A. (FR) 1980-08-12 US claimed
US-4184037-A RADIOIMMUNOASSAY BURROUGHS WELLCOME CO. (US) 1980-01-15 US claimed
US-4175078-A Cardenolide and bufadienolide derivatives of ajmaline and process for producing same Kharkovsky Naucho-Issledovatelsky Khimfo-Farmatsevtiches-Ky Institut (SU) 1979-11-20 US claimed
US-4102884-A TREATING A 3,14-DIHYDROXY-CARDENOLIDE WITH OXYGEN AND N-BROMOACETAMIDE IN THE PRESENCE OF PLATINUM, THEN WITH ETHANEDITHIOL, RANEY NICKEL STEELE CHEMICALS CO. LTD. (CA) 1978-07-25 US claimed
US-4097477-A Steroid compounds and processes thereof STEELE CHEMICALS CO. LTD. (CA) 1978-06-27 US claimed
US-4060607-A Cardenolide derivatives ETABLISSEMENTS NATIVELLE S.A. (FR) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129170-A1 EPO RECEPTOR AGONISTS AND ANTAGONISTS EPOR, MPL, PRLHR ATP1A1 4524/4885ATP1B1 4724/4885ATP1A3 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.