SCHEMBL377318

SCHEMBL377318

Cc1oc(C2=CC(CN3CCN(Cc4cc(-c5oc(C)c(C(=O)O)c5C)cc(C(=O)O)n4)CCN(Cc4cc(-c5oc(C)c(C(=O)O)c5C)cc(C(=O)O)n4)CC3)(C(=O)O)NC=C2)c(C)c1C(=O)NCCCCCCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3024502 0.99
SCHEMBL3016621 0.90
SCHEMBL13214421 0.86 DRD3 (0.35)
SCHEMBL10044305 0.81 DRD3 (0.31)
SCHEMBL13190893 0.76
SCHEMBL13234762 0.75 DRD3 (0.30)
SCHEMBL13214424 0.74 DRD3 (0.33)
SCHEMBL3021494 0.74 ALDH1A1 (0.36)
SCHEMBL3016482 0.74 ALDH1A1 (0.36)
SCHEMBL13929110 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408930-B1 BIOTINIDASE ASSAY WALLAC OY (FI) 2015-05-06 EP disclosed
US-20120045784-A1 BIOTINIDASE ASSAY Joachim Ngiamas trustee for Joachim Ngiam Trust Fund ABN 2012-02-23 US disclosed
EP-2408930-A2 BIOTINIDASE ASSAY WALLAC OY (FI) 2012-01-25 EP disclosed
WO-2010106222-A2 BIOTINIDASE ASSAY WALLAC OY (FI) 2010-09-23 WO disclosed