Urea

Urea

SCHEMBL3773480

C=CCCCCCCC=C.NC(N)=O

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
ABCC4 O15439 1/20 0.61
ALDH1A1 P00352 6/20 0.58
LMNA P02545 3/20 0.52
TSHR P16473 3/20 0.50
LPAR3 Q9UBY5 2/20 0.46
LPAR2 Q9HBW0 1/20 0.46
CYP3A4 P08684 3/20 0.40
USP2 O75604 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
FGFR4 P22455 1/20 0.40
RECQL P46063 1/20 0.40
TRPA1 O75762 2/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
SOAT1 P35610 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL3419122 0.97 MAPT (0.56) MAPTABCC4ALDH1A1LMNATSHR
Urea SCHEMBL10833770 0.90 ABCC4 (0.52) MAPTABCC4ALDH1A1LMNATSHR
Urea SCHEMBL17003979 0.88 TSHR (0.73) MAPTABCC4ALDH1A1LMNATSHR
Urea SCHEMBL9615746 0.88 TSHR (0.73) MAPTABCC4ALDH1A1LMNATSHR
Urea SCHEMBL9070468 0.88 TSHR (0.73) MAPTABCC4ALDH1A1LMNATSHR
Urea SCHEMBL8671912 0.88 TSHR (0.73) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL25269893 0.87 MAPT (0.67) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL5066976 0.87 MAPT (0.67) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL3119162 0.87 MAPT (0.67) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL3127526 0.87 MAPT (0.67) MAPTABCC4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4088440-A Transfer printing of treated cellulosics HEBERLEIN TEXTILDRUCK AG (CH) 1978-05-09 US claimed
WO-2022071465-A1 VISCOUS COMPOSITION 住友精化株式会社 2022-04-07 WO disclosed
WO-2022071463-A1 VISCOUS COMPOSITION 住友精化株式会社 2022-04-07 WO disclosed
WO-2022071473-A1 VISCOUS COMPOSITION 住友精化株式会社 2022-04-07 WO disclosed
WO-2022071461-A1 VISCOUS COMPOSITION 住友精化株式会社 2022-04-07 WO disclosed
WO-2022071474-A1 VISCOUS COMPOSITION 住友精化株式会社 2022-04-07 WO disclosed
US-7858112-B2 Percutaneous absorption system and percutaneous absorption method LINTEC CORPORATION (JP) 2010-12-28 US disclosed
US-6830726-B2 Acrylic polymer and a radiation-resistant agent (hydrogenation rosin resin for example); use in medical equipment that is radiation sterilized, for example LINTEC CORPORATION (JP) 2004-12-14 US disclosed
US-20030161869-A1 Percutaneous absorption system and percutaneous absorption method LINTEC CORPORATION (JP) 2003-08-28 US disclosed
US-6425927-B1 AQUEOUS SOLUTION OF RESIN, THERMOPLASTIC, METAL COMPOUND, SOFTENING AGENT AND EMULSIFIER DR. TH. BOEHME KG CHEM. FABRIK GMBH & CO. (DE) 2002-07-30 US disclosed
US-20020064670-A1 Radiation-resistant adhesive composition and adhesive product using the same LINTEC CORPORATION (JP) 2002-05-30 US disclosed
EP-0349241-A2 Water-absorbent resin and production process NIPPON SHOKUBAI CO., LTD. (JP) 1990-01-03 EP disclosed
US-4248938-A BONDING TO INSURE SOFTNESS AND RESISTANCE TO FATIGUE TEIJIN LIMITED (JP) 1981-02-03 US disclosed
US-4088440-A Transfer printing of treated cellulosics HEBERLEIN TEXTILDRUCK AG (CH) 1978-05-09 US disclosed
US-3989457-A APPLYING A CROSSLINKING FINISHING AGENT HEBERLEIN & CO. AG (CH) 1976-11-02 US disclosed