Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982551 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL10548401 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL9299029 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL24287565 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL9856658 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL25269893 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL3119162 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL16758454 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL3127526 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 | |
| SCHEMBL454519 | 1.00 | MAPT (0.67) | MAPTABCC4ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025751-A | Compositions and methods for treating hepatitis b virus infection | 安徽荣航生物科技发展有限责任公司 | 2022-02-08 | — | — | CN | claimed |
| CN-100551902-C | light active material | ROLIC AG (CH) | 2009-10-21 | — | — | CN | claimed |
| CN-1671648-A | photoactive material | ROLIC AG (CH) | 2005-09-21 | — | — | CN | claimed |
| CN-116650397-A | Colchicine cream and preparation method thereof | 山东新时代药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023087632-A1 | ANTI-INFLAMMATORY ANALGESIC COMPOUND AND USE THEREOF | 江苏新元素医药科技有限公司 | 2023-05-25 | — | — | WO | disclosed |
| CN-114828840-A | Improved topical compositions of colchicine | 泽威恩制药有限责任公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114656429-A | Anti-inflammatory analgesic compound and application thereof | 江苏新元素医药科技有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114025751-A | Compositions and methods for treating hepatitis b virus infection | 安徽荣航生物科技发展有限责任公司 | 2022-02-08 | — | — | CN | disclosed |
| EP-3461835-A1 | CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 | ContraVir Pharmaceuticals, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| US-8481558-B2 | Compounds to inhibit or augment an inflammatory response | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2013-07-09 | — | — | US | disclosed |
| EP-2331552-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20080045557-A1 | Administering chemokine peptides, variants, and derivatives thereof, as well as chemokine peptide analogs to modulate the migration or recruitment of leukocytes to a preselected physiological site | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD. | 2008-02-21 | — | — | US | disclosed |
| US-7238711-B1 | Compounds and methods to inhibit or augment an inflammatory response | CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD. (GB) | 2007-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045557-A1 | Administering chemokine peptides, variants, and derivatives thereof, as well as chemokine peptide analogs to modulate the migration or recruitment of leukocytes to a preselected physiological site | CCL2, CCL11, CCL5 | MAPT 4750/4885ABCC4 2633/4885ALDH1A1 4774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.