Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 7/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772296 | 0.93 | PTGDR2 (0.56) | PTGDR2F10HTR1AADRA1ADRD2 | |
| SCHEMBL3777939 | 0.90 | PTGDR2 (0.43) | PTGDR2F10HTR1AADRA1ADRD2 | |
| SCHEMBL3777935 | 0.90 | PTGDR2 (0.43) | PTGDR2F10HTR1AADRA1ADRD2 | |
| SCHEMBL3780238 | 0.89 | PTGDR2 (0.46) | PTGDR2F10HTR1AADRA1ADRD2 | |
| SCHEMBL3780242 | 0.89 | PTGDR2 (0.46) | PTGDR2F10HTR1AADRA1ADRD2 | |
| SCHEMBL3779875 | 0.88 | PTGDR2 (0.58) | PTGDR2HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3777093 | 0.88 | PTGDR2 (0.52) | PTGDR2HPGDL3MBTL1 | |
| SCHEMBL3776143 | 0.87 | PTGDR2 (0.51) | PTGDR2HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3782910 | 0.87 | PTGDR2 (0.46) | PTGDR2F10LRRK2 | |
| SCHEMBL3778394 | 0.85 | PTGDR2 (0.49) | PTGDR2HPGDHSD17B10LRRK2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928457-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-12-12 | — | — | EP | disclosed |
| US-7858640-B2 | Quinolines and their therapeutic use | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-28 | — | — | US | disclosed |
| US-20090156600-A1 | Quinolines and Their Therapeutic Use | GB005, INC. | 2009-06-18 | — | — | US | disclosed |
| EP-1928457-A2 | QUINOLINES AND THEIR THERAPEUTIC USE | Argenta Discovery Limited (GB) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007036743-A2 | QUINOLINES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156600-A1 | Quinolines and Their Therapeutic Use | NR3C1, NR3C2, NR1H3 | PTGDR2 146/4885F10 1999/4885HTR1A 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.