SCHEMBL377630

SCHEMBL377630

CN1C(=O)CNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30945566 0.88 BRPF1 (0.41)
SCHEMBL22416283 0.87 BRPF1 (0.44)
SCHEMBL11267923 0.79 BRPF1 (0.47)
SCHEMBL17982475 0.78
SCHEMBL28159 0.76
SCHEMBL11987580 0.76
SCHEMBL6858201 0.76
Hydrochloric Acid SCHEMBL21817836 0.74
SCHEMBL83965 0.73
SCHEMBL19708712 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4460301-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES Universität zu Köln (DE) 2024-11-13 EP claimed
WO-2023131576-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES UNIVERSITÄT ZU KÖLN (DE) 2023-07-13 WO claimed
CN-114945569-A Pyrrolidine derivative, and pharmaceutical composition for preventing or treating beta-amyloid or Tau-protein related diseases comprising same 延世大学校产学协力团 2022-08-26 CN claimed
US-9238640-B2 Anti-inflammatory agents RESVERLOGIX CORP. (CA) 2016-01-19 US claimed
US-9139576-B2 Aminomethyl biaryl benzotriazole derivatives MERCK SHARP & DOHME CORP. (US) 2015-09-22 US claimed
EP-2704573-A1 AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES Merck Sharp & Dohme Corp. (US) 2014-03-12 EP claimed
US-20140066443-A1 AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES MERCK SHARP & DOHME LLC 2014-03-06 US claimed
WO-2013175281-A1 USE OF SUBSTITUTED 2-PHENYL-3H-QUINAZOLIN-4-ONES AND ANALOGS FOR INHIBITING BROMODOMAIN AND EXTRA TERMINAL DOMAIN (BET) PROTEINS RVX THERAPEUTICS INC. (CA) 2013-11-28 WO claimed
US-20130281399-A1 TREATMENT OF DISEASES BY EPIGENETIC REGULATION RVX THERAPEUTICS INC. (CA) 2013-10-24 US claimed
WO-2012151136-A1 AMINOMETHYL BIARYL BENZOTRIAZOLE DERIVATIVES MERCK SHARP & DOHME CORP. (US) 2012-11-08 WO claimed
US-20020086999-A1 Certain quinoline derivatives EISAI CO., LTD. 2002-07-04 US claimed
US-20020019531-A1 Indoles EISAI CO., LTD. 2002-02-14 US claimed
EP-0976732-A1 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-02-02 EP claimed
US-5852029-A Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1998-12-22 US claimed
EP-0711292-A1 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY KOSMIN, Gerald, Emmanuel (GB) 1996-05-15 EP claimed
US-4816454-A CARDIOVASCULAR DISORDERS CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-28 US claimed
EP-0175363-A2 4,5-Dihydro-3(2H)-pyridazinones, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1986-03-26 EP claimed
US-4578224-A Method for preparation of salts of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1986-03-25 US claimed
EP-0107464-B1 METHOD FOR PREPARATION OF N-PHOSPHONOMETHYLGLYCINE STAUFFER CHEMICAL COMPANY (US) 1986-01-08 EP claimed
EP-0107464-A1 Method for preparation of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1984-05-02 EP claimed