SCHEMBL3776532

SCHEMBL3776532

NCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CA2 P00918 2/20 0.31
CA1 P00915 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28612856 1.00 LMNA (0.35) LMNACA2CA1MMP1MMP2
SCHEMBL810661 1.00 LMNA (0.35) LMNACA2CA1MMP1MMP2
SCHEMBL3778734 1.00 LMNA (0.35) LMNACA2CA1MMP1MMP2
SCHEMBL3770995 1.00 LMNA (0.35) LMNACA2CA1MMP1MMP2
SCHEMBL811215 1.00 LMNA (0.35) LMNACA2CA1MMP1MMP2
Iodide SCHEMBL3698424 0.97 LMNA (0.33) LMNACA2
SCHEMBL5519977 0.97 LMNA (0.30) LMNA
SCHEMBL4806756 0.91
SCHEMBL4806917 0.91
SCHEMBL13738326 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150225339-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2015-08-13 US disclosed
EP-2904030-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2015-08-12 EP disclosed
WO-2014053636-A1 FLUORINATED POLYMERIZABLE COMPOUND BASF SE (DE) 2014-04-10 WO disclosed
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 US disclosed
US-20090240004-A1 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-09-24 US disclosed
US-20090198000-A1 Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates EVONIK DEGUSSA GMBH (DE) 2009-08-06 US disclosed
EP-2085442-A1 Compounds containing fluoride with improved surface characteristics Evonik Degussa GmbH (DE) 2009-08-05 EP disclosed
US-20090054588-A1 Fluoride-modified additive for cementitious products, process for its preparation and use thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-02-26 US disclosed
EP-1994068-A1 FLUORINE-MODIFIED ADDITIVE FOR CEMENTITIOUS PRODUCTS, PROCESS FOR ITS PREPARATION AND USE THEREOF Construction Research and Technology GmbH (DE) 2008-11-26 EP disclosed
WO-2007104494-A1 FLUORINE-MODIFIED ADDITIVE FOR CEMENTITIOUS PRODUCTS, PROCESS FOR ITS PREPARATION AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225339-A1 FLUORINATED POLYMERIZABLE COMPOUND FRK, AFF2, AFF1 LMNA 2867/4885CA2 1277/4885CA1 607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.