Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2B1 | O94956 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.65 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | PLAU | P00749 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13010127 | 1.00 | SLCO2B1 (0.65) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL29625608 | 1.00 | SLCO2B1 (0.65) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL30566310 | 0.86 | CYP3A4 (0.61) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL29369929 | 0.85 | SLCO2B1 (0.69) | SLCO2B1MAPTHPGDKDM4EGAA | |
| SCHEMBL27161054 | 0.85 | SLCO2B1 (0.69) | SLCO2B1MAPTHPGDKDM4EGAA | |
| SCHEMBL31322137 | 0.84 | CYP3A4 (0.62) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL1067945 | 0.81 | P4HB (0.76) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL31140190 | 0.81 | P4HB (0.76) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL17363971 | 0.81 | P4HB (0.76) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 | |
| SCHEMBL30668673 | 0.81 | P4HB (0.76) | SLCO2B1CYP2C9CYP3A4ALOX15SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2214688-B1 | MANAGEMENT AND TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | CSIR (ZA) | 2018-09-05 | — | — | EP | disclosed |
| US-9061023-B2 | Management and treatment of benign prostatic hyperplasia | CSIR (ZA) | 2015-06-23 | — | — | US | disclosed |
| US-20100316748-A1 | MANAGEMENT AND TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | CSIR (ZA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316748-A1 | MANAGEMENT AND TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | BPHL, CYP17A1, CYP46A1 | SLCO2B1 3451/4885CYP2C9 623/4885CYP3A4 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.