⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437152 | 0.84 | — | — | |
| SCHEMBL4359372 | 0.82 | — | — | |
| SCHEMBL27551778 | 0.82 | — | — | |
| SCHEMBL5188324 | 0.82 | — | — | |
| SCHEMBL11514311 | 0.77 | — | — | |
| SCHEMBL312256 | 0.76 | — | — | |
| SCHEMBL27774719 | 0.70 | — | — | |
| SCHEMBL11514221 | 0.68 | GPR84 (0.50) | — | |
| SCHEMBL28018503 | 0.67 | — | — | |
| Ethylene Glycol SCHEMBL23933211 | 0.65 | TSHR (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | MARINA BIOTECH INC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9283186-B2 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140178462-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-20120135065-A1 | Amphoteric Liposomes, A Method Of Formulating An Amphoteric Liposome And A Method Of Loading An Amphoteric Liposome | MARINA BIOTECH, INC. | 2012-05-31 | — | — | US | disclosed |
| US-20100330154-A1 | AMPHOTERIC LIPOSOMES COMPRISING NEUTRAL LIPIDS | MARINA BIOTECH, INC. | 2010-12-30 | — | — | US | disclosed |
| US-20080088046-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | NOVOSOM AG (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080089932-A1 | Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome | MARINA BIOTECH, INC. | 2008-04-17 | — | — | US | disclosed |